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Comparison Of Laparoscopic Versus Open Surgical Procedure For Early-stage Endometrial Cancer

Posted on:2019-01-12Degree:MasterType:Thesis
Country:ChinaCandidate:L WangFull Text:PDF
GTID:2334330548459995Subject:Obstetrics and gynecology
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Objective: To study the effect of laparoscopic surgery and open surgery on the treatment of early-stage endometrial carcinoma.Methods: Selected 98 patients with early endometrial carcinoma,in January 2013 to January 2016 in hospital,its general data were retrospectively analyzed,postoperative pathologic staging for stage I(reference 2014 the international union of obstetrics and gynecology tumor stage FIGO vulvar cancer,cervical cancer and endometrial cancer staging guidelines of clinical staging standard),according to the operation scheme is divided into two groups,a group for the research group(60 cases),another group as control group(38 cases).In the study group,60 patients with early endometrial carcinoma were treated with laparoscopic surgery,and 38 cases of early endometrial cancer were performed in the control group.Compared two groups of the average length of hospital stay,postoperative lymph node excision quantity,operation time,intraoperative blood loss,catheter indwelling time,anus exhaust time,complication rates,relapse rate,disease-free survival and overall survival.Results: Group of 60 cases of patients with early endometrial carcinoma average length of hospital stay(8.05 ± 3.64)d shorter than the control group of 38 cases of patients with early endometrial carcinoma average length of hospital stay(13.81 ± 8.86)d,team average hospitalization time significantly shorter than the control group(P< 0.05).Among the 60 patients with early endometrial cancer,27 were resected pelvic lymph node,pelvic lymph node dissection and abdominal aortic lymph node sampling 5 cases,and the number of lymph node resection(15.13 ± 9.44).Control group of 38 cases of early endometrial carcinoma patients,27 cases of resection of pelvic lymph nodes,pelvic lymph node resection with lymph node sampling in 9,abdominal aortic lymph node excision quantity(17.11±9.24),two groups of early endometrial carcinoma patients with no obvious difference was found between the number of lymph node excision,no statistical significance(P > 0.05).Group after treatment the incidence of complications was 3.33%(2/60),the control group after treatment the incidence of complications was 7.89%(3/38),two groups of early complications after treatment in patients with endometrial cancer has no obvious difference,no statistical significance(P > 0.05).Group of 60 cases of early endometrial carcinoma patients after treatment for anal exhaust time(2.18 ± 0.75)d,the control group of 38 cases of early endometrial carcinoma patients after treatment for anal exhaust time(2.52 ± 0.92)d,two groups of anal exhaust time after early endometrial carcinoma treatment has no obvious difference,no statistical significance(P > 0.05).After treatment group of 60 cases of early endometrial carcinoma patients catheter indwelling time shorter than the control group(2.67 ± 0.64)d 38 cases of early endometrial carcinoma patients after treatment(3.42 ± 1.44)d,catheter indwelling time difference between the two groups(P < 0.05).Group of 60 cases of patients with early endometrial carcinoma intraoperatie blood loss(147.51 ± 90.26)for ml is lower than the control group of 38 cases of patients with early endometrial carcinoma intraoperatie blood loss(558.26 ± 438.65)ml,differences between the two groups was statistically significant(P < 0.05).Group of 60 cases of early operation time after treatment for patients with endometrial cancer(261.34 ±58.17)min,the control group of 38 cases of early operation time after treatment for patients with endometrial cancer(249.73 ± 65.62)min,no statistically significant differences between the two groups(P > 0.05).Postoperative follow-up of 12 months,the team the recurrence rate(0.00%),disease-free survival rate(100.00%)and overall survival(100.00%)and control group(2.63%),recurrence disease-free survival rate(100.00%)and overall survival(100.00%),two groups of early endometrial cancer relapse rate,disease-free survival and overall survival in patients with no obvious difference,no statistical significance(P > 0.05).Conclusion: The application of open surgery and laparoscopic surgery for early endometrial cancer treatment has good curative effect,resection quantity,intraoperative complications,postoperative complications,operation time and recurrence rate,disease-free survival rate and overall survival rate had no significant differences between two kinds of surgical lymph nodes;however,compared with open surgery in terms of laparoscopic surgery in the treatment of early endometrial cancer after the hospitalization time,bleeding volume,indwelling catheter time better.Laparoscopic surgery is the first choice for the treatment of early endometrial cancer,but the long-term effect of laparoscopic surgery needs further confirmation.
Keywords/Search Tags:Open surgery, Laparoscopic surgery, Early-stage endometrial cancer
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