Meta-analysis Of Recurrence Factors Related To Borderline Ovarian Tumor

Objectives: To investigate the recurrence factors of borderline ovarian tumor via Meta-analysis.Method: Rretrieve Pubmed,The Cochrane Library,Embase,CNKI,CBM,Wan Fang Database about BOT before march 2018,and collect all the research about the following six aspects: surgery type,pathological type,underwent a complete staging surgery or not,IVF treatment after fertility-sparing surgery,fertility-sparing surgery in treating stage ?~? BOT,adjuvant chemotherapy in stage ?~? BOT.All the literature were screened according to inclusion and excluding criteria,then exclude those not in conformity with the purpose of this study.At last,use RevMan 5.3 to analysis all the choosen articles.Outcome: 40 studies were searched meeting the inclusion criteria.The results of Meta-analysis showed that: 1.the recurrence rate in the laparoscopic group was not higher than the laparotomy group;2.the serous BOT recurrence rate was higher than the mucous BOT significantly;3.patients underwent unstaged surgery did not have a higher rucurrence rate when campared with staged ones;4.the recurrence rate of IVF assisted reproductive treatment patients group was not higher than not;5.the recurrence rate of patients underwent fertility-sparing surgery was higher than the radical surgery group in stage ? ~ ? BOT significantly;6.The application of adjuvant chemotherapy can not reduce the the recurrence rate in stage ?~? BOT when campared with surgery only group.Conclusion: In the treatment of borderline ovarian tumors,The laparoscopic surgery and incomplete staging surgery did not increase recurrence rate.The pathological type of serous has a higher recurrence rate than mucous.In stage ?~? BOT,fertility-sparing surgery lead to a easier recurrence,adjuvant chemotherapy after surgery cannot reduce the recurrence rate.