Survival Analysis And Clinical Features In Young Advanced Breast Cancer Patients(Aged Of?35)

Objective:To analize the survivl and compare the clinical features in young advanced breast cancer patients between different ethnic group.Methods:We colletted the data of163 advanced young breast cancer patients(aged 35 years old or less)with pathologic proof,139 patients from2010 to 2013 in the XinJiang Tumor Hospital,which are divided into two groups: Uyghur(60)and Han(79).Compare the Clinicopathological features,Condition of recurrence and metastasis,Serum index,the common relapse and metastasis sites,disease-free survival(DFS),biological indicator,the way of therapy,neutrophil—to—lymphocyte ratio(NLR)and platelet—to—lymphocyte ratio(PLT),serum tumor remarks,serum LDH and factors of survival analyzed.Results:In the two groups: Tomur size,histological grade,T stage,M stage,in Uyghur group with The recurrence and metastasis breast cancer are significantly highter than those in the Han group.Uyghur group is more likely to infringe the chest wall than Han group;The liver metastasis rate and of Uyghur patients is higher than that of Han patients.the median survival time was 28 months,and the 5-year survival rate of Uyghur was 66.67%,Han was83.54%.Univariate analysis of the 5-year survival analysis revealed that the tumor size,histological grade,the common relapse and metastasis sites,disease-free survival(DFS),CEA?CA125?NLR?PLR were significantly associated with poor outcomes.Conclusions: This study reveals nationality and histological grade,visceral metastasis,CEA ? PLR are maybe the independent factors of survival.the 5-year survival rate of Uyghur in more poor than Han.