The Research Of Professor Luo Xiuli's Clinical Experience In The Treatment Of Primary Lung Cancer

Objective: To collect and sort out the outpatient data of Professor Luo Xiuli's treatment of lung cancer,use a data analysis method to systematically study the formulas used,and create a database of lung cancer treatment medicines with relatively complete contents and data mining.Organizing Luo Xiu's clinical treatment of lung cancer diagnosis and treatment ideas,diagnosis and treatment characteristics and drug experience.In order to pass on its academic thoughts,improve the clinical efficacy of lung cancer,provide a clinical reference for dialectical treatment of lung cancer.METHODS: This study collected data on 110 patients with lung cancer who were treated by Professor Luo Xiuli from the Oncology Department of Hubei Provincial Hospital from October 2016 to October 2017.The patient's gender,age,pathological type,symptoms,and syndrome were included in the data.Types and medications were sorted out and pre-processed,an Excel data sheet for diagnosis and treatment of lung cancer was established,and SPSS 22.0 statistical software was entered.Related data was processed using frequency analysis and statistical methods and cluster analysis,focusing on the frequency of commonly used drugs and the characteristics of clinical drug use.Prof.Luo Xiuli's experience in clinical trials analyzed,summarized and summarized the data results.Results: A total of 110 cases were collected after standard screening,including 67 males(60.9%)and 43 females(39.1%).Age 38-83,average 63 years old.According to frequency analysis,the top 10 symptoms with the highest frequency in all visits were cough,fatigue,anorexia,cough and sputum,gasping,sweating,loose stools,coughing a small amount of jaundice,chest pain,and abdominal distension.A total of 192 drugs were used.The top 20 herbal medicines with the highest frequency were Astragalus membranaceus,Rhizoma Rhaponantaria,Radix Glycyrrhizae,Atractylodes Rhizome,Shi Shang Bai,Herba Agrimonia,Pinellia ternate,Reed Root,Tian Kuizi,Bai Ying,Loranthaceae,and Earthworm.,tree tongue,loquat leaves,coltsfoot flowers,asters,cat's claw grass,barley,mountain sagittifolia,lotus root.In the 110 visits,they accounted for 3.3%,2.8%,2.6%,2.5%,2.5%,2.4%,2%,2%,1.9%,1.9%,1.9%,1.8%,1.8%,1.8%,1.8,respectively.%,1.8%,1.8%,1.7%,1.7%,1.6%.In several common types of lung cancer,the frequency is from high to low,namely the heat and sputum lung syndrome,the cult poison accumulation lung syndrome,the spleen deficiency dampness syndrome,the lung and spleen qi deficiency syndrome,the deficiency of both qi and yin,and the syndrome of phlegm and stasis.Yin deficiency heat card.The frequencies were 22.4%,18.7%,17.2%,14.2%,11.9%,11.2%,and 4.5%,respectively.After classifying the efficacy of drugs,according to statistical analysis of frequency,treatment of lung cancer with Qingrejiedu,Qingre Sanjie,phlegm-reducing,and tonic drugs was mainly performed.The drugs were classified according to the nature of the frequency of the statistics,you can see that the drug taste is mainly bitter Gan Ping,the main drug to cold temperature,return to the lung,liver,spleen,stomach,kidney and mostly.The cluster analysis was performed on the drugs with a frequency of more than 8 times in 192 Chinese herbs.Three large groups of clusters have been obtained,which are frequently added or subtracted based on clinical practice as follows:(1)Foundations based on righting support: Astragalus membranaceus,Atractylodes macrocephala,and licorice;(2)Antipyretic and anti-tumor effects The main bases are: stone cypress,earthworm worm,cat's claw grass,mulberry parasitic,tree tongue,shanxi mushroom,sarcophagus;(3)the basis of symptomatic cough and phlegm-based treatment: Aster,coltsfoot,reed rhizome,loquat leaves,vine root,agrimony grass.Four small cluster groups were obtained as follows:(1)fried malt,Shenqu,Jiaoshan,Amomum villosum,woody,Codonopsis pilosula;(2)Coptis chinensis,Huangqi,Anemarrhena,Almond,Citrus aurantium,Campanulaceae;(3)Cockroach Ren,peach,winter melon seeds;(4)Scrophulariaceae,white silkworm,Ophiopogon japonicus.In the smallest category,we got 9 pairs of medicines: Sanling + Curcuma,Rhizoma Imperatae + Houttuynia,Angelica + Chuanxiong,Aster + Coltsfoot,Scutellaria barbata + Hedyotis,Citrus + Pinellia,Amomum + woody,coke hawthorn + fried malt,mulberry + tree tongue.Conclusion: It has been found through research that the disease location of lung cancer is mainly in the lungs and involves liver,spleen,stomach and kidney.Pathological factors are mainly "heat,sputum,poison,wetness,and deficiency",among which deficiency of righteousness is the basis of lung cancer.Heat and poison are closely related to the incidence of lung cancer.Clinically,the type of syndrome on the clinical syndrome is phlegm-inspiring lung syndrome,cult poison accumulation lung syndrome,spleen deficiency dampness syndrome,and lung-spleen-qi deficiency syndrome.The main treatment is detoxification,detoxification,phlegm-resolving,phlegm-resolving phlegm,spleen-invigorating and spleen-invigorating.Lord,according to the patient's different syndromes,appropriate with cough and asthma,digestion and stomach,Tongluozhitong,nourishing yin,bleeding,convergence Guse,Wentong meridians.