Distribution Law Of TCM Syndromes In Acute Exacerbation Of The Chronic Obstructive Pneumonia And Its Correlation Research Of CRP?PCT?D-Dimer?Pulmonary Function

Objective:In order to analyze Distribution Law of TCM Syndromes in acute exacerbation of the chronic obstructive pneumonia,and to explore its relation with CRP?PCT?D-Dimer biochemical indicator and pulmonary function,providing more evidence for future TCM argumentation of this disease.Methods:From February 2016 to December 2017,120 patients with acute exacerbation of chronic obstructive pulmonary disease in the Department of respiration,Fuzhou Traditional Chinese Medicine Hospital were selected as the subjects.The general information and four diagnostic data of TCM were collected,and the biochemical indexes of CRP?PCT?D-Dimer and lung function were examined.The four diagnosis information was collected into the health status identification system of the Fujian University of traditional Chinese medicine(scientific research edition).The distribution of TCM syndrome in the acute exacerbation period was analyzed after the system operation,the extraction of the disease position and the syndromes of the disease,and the correlation of the TCM syndromes with CRP?PCT?D-Dimer and lung function was studied.Results:1.Eat Feigan thick greasy and phlegm,dampness,heat,blood heat syndrome patients;smoke and heat,blood heat,yin deficiency with greater correlation;the age of onset is related to Qi deficiency,heart,blood deficiency,blood stasis and yang deficiency syndrome;smoking age is related to Qi deficiency,heat,heart,blood deficiency and yang deficiency syndrome.2.1n the analysis of biochemical indexes of acute exacerbation of chronic obstructive pulmonary disease,it was found that 83.3%CRP increased in patients with acute exacerbation of chronic obstructive pulmonary disease,21.7%PCT increased and 78.3%D-Dimer increased.The correlation analysis between the biochemical indexes and the syndrome scores showed that the CRP and PCT values were positively correlated with the lung and the table(P<0.05,r>0),and the D-Dimer value was positively correlated with the lung,spleen,heart and kidney of the disease position syndrome(P<0.05,r>0).The value of CRP and PCT showed significant positive correlation with disease syndrome fever,blood heat,phlegm,external wind,dryness,deficiency and yin deficiency(P<0.01,r>0).CRP,PCT value and disease syndrome were negatively correlated with Qi deficiency,Yang deficiency,cold,blood deficiency and drinking(P<0.05,r<0).The D-Dimer value was positively correlated with syndrome factor qi stagnation,blood stasis,Qi deficiency and yang deficiency(P<0.05,r>0),and there was a significant positive correlation with disease syndrome qi stagnation and blood stasis(P<0.01,r>0).3.All the indexes of lung function in patients with acute exacerbation of chronic obstructive pulmonary disease were normal distribution(P<0.05),and the measured values of lung function indexes were all lower than those of normal,and the percentage of the estimated value decreased;from the grade distribution,there were 56 cases of mild frequency(46.67%),22 cases(18.33%)with moderate frequency,13 cases(10.83%),26 cases(21.67%),3 cases(2.50%);there was a significant negative correlation between various indicators of lung function and age,smoking duration,smoking volume and duration of onset(P<0.05,r<0).There was no statistical correlation between FEV1/pre%and disease location,lung,spleen,kidney,exterior,heart and liver(P>0.05);It is positively correlated with disease syndrome,such as phlegm,dampness,Qi deficiency,Yang deficiency,cold,yin deficiency,drinking,qi stagnation and blood stasis(P>0.05).Conclusion:1.It is a risk factor for phlegm,dampness,heat and blood heat syndrome in patients with acute exacerbation of chronic obstructive pulmonary disease.Smokers in acute exacerbation of chronic obstructive pulmonary disease are more obvious than those in non-smokers.2.The longer the course of disease and the longer the smoking age,the more likely the diagnosis of cardiac syndrome is.3.The metabolic disorder of the three fluid in lung,spleen and kidney is the root cause of chronic obstructive pulmonary disease.The invasion of exogenous pathogens is the main cause of acute exacerbation.4.Lung,spleen,kidney,heart,Qi deficiency,qi stagnation,blood stasis and yang deficiency are significantly correlated with D-Dimer in acute exacerbation of chronic obstructive pulmonary disease.5.Heat,yin deficiency and blood heat syndrome are positively correlated with CRP and PCT.There is a negative correlation between cold,Qi deficiency,Yang deficiency,blood deficiency,yin and CRP and PCT.6.Age,smoking duration,smoking volume and age of onset are risk factors of lung function decline.