| Purpose: By using questionnaire,retrospective study of chronic kidney disease Changchun area(Chronic Kidney Disease,CKD)patients self management status(including proteinuria,blood pressure,blood sugar level of management and intervention measures),correlation analysis speed of its management level and the development of CKD,risk factors for further analysis of the CKD process Changchun influence area and to provide the basis for clinicians to provide delay the development of CKD management strategy.Method: 1,From September 2014 to December 2016 in the Affiliated Hospital of Changchun University of Traditional Chinese Medicine from outpatient treatment area and dialysis room for treatment of end-stage renal disease(End Stage Renal Disease,ESRD).2 Patients,using self-made questionnaire,demographic data and clinical data of.3 Patients were collected,the count data expressed as a percentage,urine protein,blood pressure,blood glucose level and CKD management the pace of progress correlation using Pearson linear correlation and Logistic regression analysis.Results: 1,In this study,a total of 300 patients with ESRD were investigated,286 were effective,35.31% were chronic glomerular diseases,34.97% were hypertensive nephropathy,and ESRD were diabetic nephropathy(29.72%.).2,On proteinuria in patients with CKD,blood pressure(systolic blood pressure),blood glucose(fasting blood glucose)the correlation between the management level and the development of CKD:(1)when the "24 hour urinary protein quantitative" 1.0g/24 h ",R-0.945,P 0,showed a significant negative correlation,when the" 24 hour urinary protein quantity is greater than or equal to 1.0g/24 h "when the value of R,-0.940,P 0,showed a significant negative correlation,indicating that 24 hour urinary protein quantitative management better,CKD the rate of progress is slower,the longer the time to enter the ESRD;(2)when the blood pressure(systolic blood pressure)is less than or equal to 130/80 mmH G,R value-0.516,P value of 0.006,negative correlation when the blood pressure(systolic blood pressure)130/80-160/100 mmHg,R value-0.314,P value of 0.043,negative correlation when the blood pressure(systolic blood pressure greater than 160/100 mmHg,R value-0.437,P value of 0.029,negative correlation shows that when the blood pressure(SBP)management,speed CKD slow progress,time delay into the ESRD;(3)when the blood glucose(fasting blood glucose)" 8.0mmol/L ",R-0.831,P 0 0,when the blood glucose was negatively correlated(fasting blood glucose)than 8.0mmol/L,R value-0.553,P value of 0,negative correlation,indicating when the blood glucose(fasting blood glucose)management,speed CKD slow progress,time delay into the ESRD.(1)when the " 24 hour urinary protein quantitative " 1.0g/24 h " and " 24 hour urinary protein quantity is greater than or equal to 1.0g/24 h when using different interventions,24 hour urinary protein quantitative management level and development speed of CKD correlation: R value-0.952,P value 0,R value-0.908,P value 0,R value-0.920,P a value of 0-0.769,R value,P value of 0,negative correlation,illustrate the application of different intervention measures,can slow the speed of CKD progress,but the combination of Chinese and Western medicine treatment effect on the speed of CKD more progress;(2 ")blood pressure(SBP)less than 130/80 mmHg when using different interventions,24 hour urinary protein quantitative management level and development speed of CKD correlation: R value-0.618,P value 0.019,R value-0.770,P value 0.006,illustrate the application of different intervention measures,can slow the speed of CKD progress;when the blood pressure(systolic blood pressure 130/80-160/100mmHg)and blood pressure(systolic blood pressure greater than 160/100 mmHg when blood pressure(SBP)speed management level and progress of CKD had no statistical significance(P > 0.05)(;3)"when blood glucose(fasting blood glucose)than 8.0mmol/L,application of different interventions,blood glucose(fasting blood glucose)and CKD progression rate correlation: R value-0.556,P value 0.009,R value-0.635,P value 0.011,illustrate the application of different intervention measures,can delay the development of CKD speed.4,Compare the speed of CKD patients with different intervention measures on the CKD(1): " the 24 hour urinary protein quantitative < 1.0g/24 h,t = 2.384,P = 0.023,when the " 24 hour urinary protein quantity is greater than or equal to 1.0g/24 h when t = 2.383,P = 0.023,indicating treatment on the basis of adhering to the traditional Chinese medicine treatment can the rate of progression of CKD,extending into the ESRD time;(2)when the blood pressure(systolic blood pressure)is less than or equal to 130/80 mmHg " and " blood pressure(SBP)130/80-160/100 mmHg " 2.308,t value,P value 0.031,t value 5.157,P value 0,that on the basis of the basic treatment of Chinese medicine can better adhere to the rate of progression of CKD,extending into the ESRD time,when the blood pressure(systolic blood pressure greater than 160/100 mmHg,t value-0.555,P value 0.586,no statistical significance(P > 0.05);(3)when the blood glucose(fasting blood glucose)"8.0mmol/L",Z-0.910,P 0.363,was not statistically significant(P > 0.05),when the blood glucose(fasting blood glucose)or 8.0mmol/L,t value 2.079,P value of 0.045,indicating that in the foundation of treatment,adhere to traditional Chinese medicine treatment,can better delay the progress of CKD,and extend into the ESRD time.5,Regression analysis of risk factor of CKD progression: 24 hour urinary protein,high blood pressure(SBP),diabetes(fasting blood glucose)are risk factors affecting the development of CKD,the P values were 0.000,0.000 and 0,24 hour urinary protein quantitative and systolic blood pressure,fasting blood glucose level of the air,CKD the pace of progress.Conclusions: 1,Our hospital is currently in the cause of ESRD in the cause of chronic glomerular disease mainly,hypertensive nephropathy and diabetic nephropathy secondary,and our cause of ESRD consistent with the cause.2,The local CKD patients,proteinuria,hypertension(systolic blood pressure),blood glucose(fasting blood glucose)was significantly correlated with the progression of CKD speed management level,24 hour urinary protein,blood pressure(systolic blood pressure),blood glucose(fasting blood glucose)are risk factors affecting the progression of CKD,that of proteinuria,hypertension(systolic blood pressure),blood glucose(fasting blood glucose)management is good,can delay the progression of CKD,extending into the ESRD time,on the whole,the local CKD patients adhere to treatment of traditional Chinese medicine treatment on the basis of,can better the rate of progression of CKD,extending into the ESRD time.3,In the management of patients with CKD,urge CKD patients to strengthen the management of proteinuria,hypertension(systolic blood pressure),diabetes(fasting blood sugar),in the treatment,adhere to traditional Chinese medicine treatment,can delay the progress of CKD,and extend into the ESRD time. |
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