Clinical Analysis Of 210 Cases Of Borderline Ovarian Tumors

Objective:The study aim to investigate the clinicopathological characteristics and risk factors for recurrence of epithelial ovarian borderline tumors.Methods:It was a retrospective study involving 210 cases of BOTs clinical datas in the tumor hospital of Shanxi province from January 2001 to December 2014.The effects of type of surgery,clinical characteristics,pathologic characteristics and preoperative examination were examined on recurrence factors.Results:1?The mean age of 210 patients was 41±16 years old,and 56 patients with fertility requirements2?49.05%(103/210)of patients were abdominal pain,abdominal distension,and38.57%(81/210)of patients were asymptomatic found in the physical examination.3?91 patients(48.40%)had a CA125 level above 35 IU/ml,53 patients(30.81%)had a CA199 level above 37 IU/ml,the difference of the elevated proportion between histological types was statistically significant(P<0.05).The median diameter of the mucous mass was 17.23 cm,and the median diameter of the serous mass was 8.23 cm,and the difference of the diameter of the mass between the two groups was statistically significant(P<0.05).4?The accuracy rate of intraoperative frozen diagnosis was 75.91%(104/137),and the accuracy rate of serous borderline tumors was about 89.19%(66/74),and the accuracy rate of mucinous borderline tumors was 60%(33/55),and the difference of accuracy of intraoperative frozen diagnosis between the two groups was statistically significant(P<0.05).5 ? The most common histological type:Serous borderline tumors in 86 cases(40.95%),mucinous borderline tumors in 90 cases(42.86%),mix-cell borderlinetumors in 21 cases(10%).Pathological staging:IA stage had 142 cases(67.62%),above IA stage in 68 cases(32.38%),most of the patients in early stage.Postoperative chemotherapy were performed to 47 patients(22.38%)with above stage II and cyst rupture.6 ? The mean follow-up time was 61.2 months,there were 23 patients with recurrence indicating recurrence rate of 11.27%.Logistic regression analysis showed that risk factors for recurrence were micropapillary pattern,age and above IA(P<0.05).The postoperative pregnancy rate was 56.60%.Conclusions:Epithelial ovarian borderline tumors mainly occur in young wome,at an early stage,and have a great prognosis.Preoperative diagnosis of BOTs remains difficult.Young patients with fertility intention could be treated with conservative surgery,and the pregnancy rate is still high.For the young,micropapillary pattern and high stage patients that show higher recurrence rates,it need follow closely to guard the disease returns.