Analysis Of Blood Glucose And Related Factors In T2DM Patients With Sleep Disorder Accompanied With Anxiety And Depression

ObjectiveObjective to investigate the effects of sleep disorders combined with anxiety and depression on blood glucose and related indexes in patients with type 2 diabetes mellitus.MethodsThe Department of endocrinology of Affiliated Hospital of Qinghai University randomized 400 people who had been diagnosed as T2 DM patients(including 152 men and 248 women)from Dec,2015 to Dec,2016,a questionnaire survey was conducted on selected people about PSQI、SDS、SAS.According to the existing situation of sleep quality and anxiety and depression were divided into four groups,were collected using insulin recorded sex age course and height,weight,SBP,DBP,FPG,PBG,HbA1 c,FINS,fasting C peptide,the research object etc..And use formula to calculate BMI,HOMA-B,HOMA-ISI,HOMA-IR.Statistical analysis using SPSS19.0 completed.ResultsSimple sleep disorder group,the anxiety and depression group,anxiety and depression with sleep disorder group compared with type 2 diabetes group,The level of FPG,PBG,HbA1 c,fasting C peptide were increased(P<0.05),HOMA-IR decreased(P<0.008),HOMA-ISI decreased(P<0.008).Simple sleep disorder group,simple anxiety and depression,anxiety and depression with sleep disorder group,among the three groups,The level of FPG,PBG,fasting C peptide had no significant difference(P>0.05),HOMA-ISI and HOMA-IR showed no significant difference(P>0.008).Sleep disorder with anxiety and depression group than the simple sleep disorder group,simple anxiety depression group had higher HbA1 c level(P<0.05);type 2 diabetes,Among simple sleep disorder group,simple anxiety depression,anxiety and depression with sleep disorders,there are no significant difference between the use of insulin(P>0.05).ConclusionSleep disorders,anxiety and depression have influenced on FPG,PBG,HbA1 c,fasting C peptide,HOMA-IR and HOMA-ISI in patients with type 2 diabetes mellitus,and increase the levels of FPG,PBG,HbA1 c,fasting C peptide and HOMA-IR,and decrease HOMA-ISI.In patients with type 2 diabetes mellitus,the prevalence of sleep disturbances associated with anxiety and depression is higher than that of anxiety,depression and sleep disturbances.