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Investigation Of Nutritional Status In 80 Patients With Tumor Chemotherapy

Posted on:2018-09-29Degree:MasterType:Thesis
Country:ChinaCandidate:Y MengFull Text:PDF
GTID:2334330536463040Subject:Nutrition and Food Hygiene
Abstract/Summary:PDF Full Text Request
Objective:This research use the nutritional risk screening 2002 and global assessment of nutrition risk screening and nutrition status of 80 cases of patients with cancer chemotherapy and for evaluation of nutritional status,and to investigate the nutritional support in patients with malnutrition.Methods:1 This study randomly selected 80 patients with malignant tumor chemotherapy in Xingtai People’s Hospital from January 2016 to December 2016,including male and female,with a total of 32 cases,and to meet the inclusion criteria and signed confidentiality of patients with nutritional risk screening 2002 and subjective assessment of the overall nutritional risk screening,nutritional status assessment and nutritional intervention survey.2 SPSS 19 statistical software was used to analyze the data of this study.The research data was tested for normality and homogeneity of variance test,meet the test of normality and homogeneity of variance test measurement data(standard deviation)to represent and used t test to indicate,count data was using frequency,percentage or ratio of said composition,for the comparison of three and more than three independent samples,the single factor variance of complete independent multi sample comparison should be used for statistical analysis.Did not conform to normality test and homogeneity test of variance,using multiple independent samples comparison Kruskal-Wallis H nonparametric test and the need for 22 comparison using rank transition variance analysis for statistical analysis.If the correlation factors were in accordding with bivariate normality test,the Pearson linear correlation analysis was used,while the Spearman rank correlation was used to carry out statistical analysis.a=0.05 as the test level,P<0.05 showing that the difference was statistically significant.Results:1 A total of 80 patients with malignant tumors were included in this study,including: male,female,gastric cancer,gastric cancer in 22 cases,colorectal cancer in 27 cases,liver cancer in 17 cases,lung cancer in,and malignant tumor in our patients in stage I,stage II in 16 cases,stage III and stage IV in 64 cases(n =14).2 80 cases of nutritional risk of patients with malignant tumor incidence rate was 63.75%,the tumor type and the incidence of nutritional risk correlated significantly(P<0.05),digestive tract malignant tumor incidence of nutritional risk was significantly higher than that of non malignant tumor of digestive tract;(age<70 years were divided into two groups and more than 70 years old)and tumor stage(divided into I,II and III,IV)rate of two groups had no significant correlation with nutritional risk(P>0.05).3 In this study,7(8.75%)patients with tumors of BMI<18.5kg/m2 were enrolled in the study.There were 25 cases tumor patients in accordance with hemoglobin and below standard values(31.25%);according to the standard of albumin,57 cases(71.25%)with albumin below 35g/L were evaluated qualitatively according to PG-SGA.According to PG-SGA qualitative evaluation,A grade tumor patients have 21 cases(26.25%),B grade tumor patients have 45 cases(56.25%),C grade tumor patients have 14 cases(17.50%).4 The nutritional index BMI,TSF,Hb and ALB were significantly different between patients with severe malnutrition and mild / moderate malnutrition(P<0.05),The nutritional indexes of patients with severe malnutrition were significantly lower than those of the latter two groups,and the traditional nutritional indicators of patients with severe malnutrition group were gradually increased.There was no significant difference in MAMC index between three groups of patients with severe malnutrition and mild / moderate malnutrition and good nutrition(P>0.05).5 Liver cancer,lung cancer,gastric cancer,the nutritional status of patients with colorectal cancer,compared to the results,the difference was statistically significant(P<0.05).Among them,the proportion of malnutrition in colorectal cancer was the highest in this study,reaching 88.5%(severe malnutrition accounted for 23.1%,mild to moderate malnutrition accounted for 65.4%);Gastric cancer accounted for 86.9%(severe malnutrition accounted for 21.7%,mild to moderate malnutrition accounted for 65.2%);the lowest proportion of malnutrition in lung cancer patients,only 42.9%(severe malnutrition accounted for only about 7.2%,light and moderate malnutrition accounted for 35.7%).6 Before chemotherapy,80 patients with malignant tumor were compared to chemotherapy,Nutrition indicators of TSF,propagated,Hb,PG-SGA quantitative evaluation index score,MAMC differences were statistically significant(P<0.05),namely after chemotherapy nutrition index TSF,propagated,Hb,PG-SGA quantitative evaluation score,MAMC than patients before chemotherapy.The differences in weight and BMI were statistically significant(P > 0.05)before and after chemotherapy.7 80 cases of tumor patients according to PG-SGA qualitative evaluation group: good nutrition group patients without nutritional support;mild to moderate malnutrition group of patients without nutritional support in 36 cases(80%),2 cases of enteral nutrition support(4.4%),parenteral nutrition support in 7 cases(15.6%);severe malnutrition group of patients without nutritional support in 7 cases(50%),2 cases of enteral nutrition support(14.3%),5 cases of intestinal supporters of parenteral nutrition(35.7%),three groups of patients with nutritional support compared,the difference was statistically significant(P < 0.05).8 In this study,80 patients with malignant tumors were evaluated with PG-SGA and NRS 2002 methods for nutritional assessment in two cases.According to the PG-SGA standard for the qualitative evaluation of light in malnutrition patients and patients with severe malnutrition were that the presence of malnutrition;NRS2002 score more than NRS2002 evaluation standard 3 points that exist malnutrition,analysis using two evaluation methods of 80 cases with the detection rate of malnutrition.The results of the study showed that the malignant tumor patients with malnutrition positive rate was 73.75% by PG-SGA method,and the use of NRS method on 2002 malignant tumor patients with malnutrition positive rate of only 63.75%,compared to the two groups there were statistically significant differences(P<0.001).By using the method of PG-SGA positive in malnourished patients with 10 cases using the NRS2002 method for evaluation of normal nutrition,including mild to moderate malnutrition patients were 7 cases,severe malnutrition group 3 cases;and the use of NRS2002 methods of positive detection of malnutrition in patients with 2 cases to evaluate the use of PG-SGA qualitative assessment of normal nutrition.9 In 80 cases of malignant tumor patients with nutritional indexes of ALB,Hb,BMI,MAC,MAMC,TSF and PG-SGA score of quantitative Spearman correlation analysis showed negative correlation existed in various nutritional indexes and PG-SGA quantitative score,the difference was statistically significant(P<0.05).Conclusions:1 Compared with the NRS 2002 method,the PG-SGA method is a more suitable,more accurate,more ideal for the nutritional status evaluation of the nutritional status of malignant tumors,which can be implemented specifically for assessment of nutritional status in patients with malignant tumors.2 Chemotherapy can affect the nutritional status of patients with malignant tumors,after chemotherapy,most patients will appear a decline in conventional nutritional indicators,that is,the nutritional status of the decline.3 The incidence of malnutrition was higher in patients with malignant tumor,so we should use PG-SGA method to evaluate the nutritional status of patients with malignant tumor of chemotherapy.4 A considerable number of malnourished patients did not receive the appropriate nutritional support,and the proportion of parenteral nutrition support was higher than that of enteral nutrition support.
Keywords/Search Tags:Nutritional Risk Screening 2002, Patient subjective overall assessment, Malignancy, Malnutrition, nutritional support
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