The Correlation Study Of Traditional Chinese Medicine Syndrome Differentiation Of Chronic Heart Failure And Bilirubin,NT-pro BNP,hs-cTNI

Objective:Through testing the bilirubin,NT-pro BNP,hs-cTNI levels of patients with chronic heart failure(CHF),we explore the correlation among the level of bilirubin,NT-pro BNP and hs-cTNI,traditional Chinese medicine(TCM)different syndrome of CHF and severity of heart failure.Method:Choose 60 patients according with the standard and 30 patients without heart failure who in qilu hospital of shandong university during June 2016 to February 2017.Collecting basic data,disease situation symptoms and signs,tongue and pulse condition,Medical history and auxiliary examination of patients when they in the hospital.Then all the patients are divided into two clinical types of TCM syndrome:qi deficiency and blood stasis and heart-kidney yang deficiency.According to the cardiac function standard of New York Heart Association.We divide patients into two groups: grade I-II and grade III-IV.We analyze these data through the statistics software SPSS l7.0.Result:1.Chronic heart failure group and control group in gender,age,systolic pressure,diastolic blood pressure,fasting blood sugar,triglyceride,low density lipoprotein cholesterol(ldl-c),cereal third transaminase on clinical indexes such as undifferentiated(P > 0.05).But glutamic oxalacetic transaminase of chronic heart failure group is higher than the control group(P = 0.02).2.NT-proBNP level of heart failure group is significantly higher than that of control group(P < 0.01)and NT-proBNP level of cardiac function grade III-IV are significantly higher than grade I-II group(P < 0.01).Bilirubin,hs-cTNI levels of cardiac function grade III-IV are significantly higher than grade I-II group and the control group(P < 0.01),but there is no difference in the level of patients in grade I-II group and the control group(P > 0.05).3.NT-proBNP level of heart-kidney yang deficiency syndrome patients and qi deficiency blood stasis are significantly higher than that of control group(P < 0.01)and NT-proBNP level of heart-kidney yang deficiency syndrome patients are significantly higher than qi deficiency blood stasis type(P < 0.01).Bilirubin,hs-cTNI levels of heart-kidney yang deficiency syndrome are significantly higher than qi deficiency blood stasis type and the control group(P < 0.01),but there is no difference in the level of qi deficiency blood stasis type and the control group(P > 0.05).4.Serum total bilirubin is positively related with the NT-proBNP(0<r<1,P<0.01),Serum total bilirubin was positively correlated with the hs-cTNI,(0<r<1,P<0.01),the NT-proBNP was positively correlated with the hs-cTNI(0<r<1,P<0.01).Conclusion: 1.NT-proBNP patients with chronic heart failure were significantly higher than normal group.But with the reduction of cardiac function NT-proBNP level of grade III-IV patients is further improved and significantly higher than that of grade I-II patients.Bilirubin and hs-cTNI levels of chronic heart failure patients at grade I-II has no obvious improvement.At grade III-IV,both are significantly improved than normal group.2.NT-proBNP level of heart-kidney yang deficiency syndrome patients are significantly higher than that of patients with qi deficiency blood stasis type and normal group and NT-proBNP level of qi deficiency and blood stasis syndrome patients are significantly higher than normal group.Bilirubin,hs-cTNI levels of heart-kidney yang deficiency syndrome patients are significantly higher than that of patients with qi deficiency blood stasis type,but there is no difference in the level of patients with qi deficiency and blood stasis and normal person.3.Bilirubin,NT-proBNP and hs-cTNI are positively related with each other.