Clinical Efficacy Comparison Of Neuroendoscopic And Neuronavigation Assisted Microsurgery For Single-nostril Transsphenoidal Pituitary Adenoma

Objective: To explore the clinical efficacy,advantages and disadvantages of neuroendoscopic and neuronavigation assisted microsurgery for single-nostril transsphenoidal pituitary adenoma.Methods: Clinical data of 54 patients with pituitary adenomas were randomly assigned,including 30 patients were treated by neuroendoscopic endonasal transsphenoidal surgery(neuroendoscopy group)and 24 treated by neuronavigation assisted endonasal transsphenoidal(navigation microsurgery group).The rate of postoperative complications,the postoperative hospital stay,operation time,blood hormone levels and total tumor resection rate of the two groups were analyzed.Results: There were no significant differences in postoperative complication rate and tumor total removal rate between the two groups(P>0.05).The operation time of the navigation microsurgery group was less than the neuroendoscopy group,but the postoperative hospital stay of endoscopy group was less than navigation microsurgery group(P<0.05).Conclusions: The clinical efficacy of euroendoscopic and neuronavigation assisted microsurgery for single-nostril transsphenoidal pituitary adenomas are similar,and the treatment should be executed according to the condition of patients.