| Objective: we know that the specific pathogenesis of cervical dystonia is not clear,in order to understand the mechanism,we used voxel-mirrored homotopicconnectivity(VMHC)to quantify the functional changes between hemispheres of the brain in cervical dystonia(CD)patients.Methods: 21 patients of CD and 21 healthy controls(sex-,age-,education-matched)were employed in this study.We used the VMHC method to analyse the functional magnetic resonance imaging data and made correlation between the VMHC values and severity of symptom,clinical course.Results:Compared with the healthy controls,the CD patients had lower VMHC in the precuneus and the medial frontal gyrus(P<0.05).No significantly correlation between values of VMHC,clinical course,severity of symptom(P>0.05).Conclusion: The incidence of CD may be related to the control abnormalities of precuneus and the medial frontal gyrus;and this abnormalities may be involved in the onset of CD via the default mode network and sensorimotor integration network. |
