Robot-asisted Surgery Versus Conventional Laparoscopic Surgery For Endometrial Cancer:A Meta-analysis

Objective: To compare perioperative outcomes between robot-assisted surgery(RAS)and conventional laparoscopic surgery(CLS)for the treatm ent of endometrial cancer by conducting a meta-analysis.Method: Search strategy was developed in accordance with the requ irements of the Cochrane Collaboration Handbook.We searched PubMed?Cochrane?Embase?WanFang?CBM?CNKI?VIP up to December,2016.Studies clearly documenting a comparison between RAS and CLS for pati ents with endometrial cancer were included.Rev Man5.1 sorwares was us ed for Statistical analysis.Comprehensive evaluation the value of RAS in the treatment of endometrial cancer.Result: 901 literatures was searched firstly,only 22 trials met the in clusion criteria and 4324 patients in total(RAS 2071,CLS 2253).Meta-analysis showed that: RAS was associated with lower intraoperative visce ral injuries(OR:0.28;95%CI:0.18—0.45;P<0.00001),lower conversion rate(OR:0.28;95%CI:0.18—0.45;P<0.00001),lower EBL(MD:-71.2;95%IC:-96.33—-46.06;P<0.00001),shorter hospital stay(MD:-0.49;95%IC:-0.7—-0.27;P<0.00001)and more cost(MD:14.37;95%CI:13.71—15.02;P<0.00001)compared to CLS.The operation time(MD:5.22;95%CI:-16.94—27.38;P=0.64)and TLNH(MD:1.06;95%CI:-2.95—5.07;P=0.6)showe d no significant differences between RAS and CLS.Conclusion: RAS is a feasible and effective surgical approach that m ay be superior to CLS for the treatment of endometrial cancer,with lowe r EBL,lower conversion rate and lower intraoperative visceral injuries.Fur ther prospective randomized trials are required to validate our findings.