The Study Of Rabies Epideiologyn In Guangxi And The Injured Crowd Dy Animals Exposure And Effectveness In Some Areas

Objective1.To describe the epidemiological characteristics of rabies in Guangxi from2006 to 2016.2.To analyze the epidemiological characteristics of the groups injured by animals and the prevention and disposure conditions after the rabies exposure in the city of Qin zhou and Fangchenggang in Guangxi.3.To evaluate the effectiveness of the prevention and control measures of rabies in Guangxi and put forward the prevention and control strategies and Suggestions for rabiesMethods1.Analysis of epidemic characteristics: in this study,the data of rabies cases in Guangxi province from 2006 to 2016 were collected from China Disease Prevention and Control information system.And the morbidity,mortality and the three intervals distribution of rabies were analyzed.2.Investigation of the injured crowd by animals: Qinzhou,Fangchenggang City choose a city-level CDC prevention clinic respectively,to analyze the characteristics of three intervals distribution in the injured crowd,injured areas and characteristics of wounded animal,as well as prevention of treatment after exposure of clinic by descriptive statistical methods.3.Epidemiological ecology research: three cities(Guigang,Yulin and Chongzuo City)were selected in rabies high,medium and low incidence areas of Guangxi province respectively,Survey area of the questionnaire survey6 included all the new rural cooperative institutions,all disease prevention and control centers and canine clinics,Bureau of animal husbandry in the three city.The studying targets included the amount of rabies vaccine,the amount of reimbursement for passive immunization agents,the number of reimbursements,the use of rabies vaccine and rabies passive immunization preparations,the number of outpatient visits,the immunization density of dogs,and the use of veterinary vaccines.The correlation between the incidence of rabies and other factors in tri-city was analyzed.Result1.From 2006 to 2016,2978 cases of rabies were reported in Guangxi province.Guangxi total morbidity number respectively in each of the 518 cases,493cases,324 cases,303 cases,286 cases,227 cases,163 cases,125 cases,111 cases and 56 cases.the cumulative incidence of 1.112/10,1.045/10,0.780/10,0.673/10,0.624/10,0.621/10,0.488/10,0.348/10,0.265/10,0.234/10,0.117/10.The number of patients with HFMD accounted for 0.07% of the legal infectious diseases and 0.17% of B class infectious diseases.In all cases,there were 2975 dead cases,the fatality rate were 99.96%.2.From the time distribution,rabies cases were reported all year round in Guangxi province.peak period of disease was July to October from 2006-2016.From the regional distribution,Especially the rabies exposure treatment costs include the new rural cooperative after 2013,the number of rabies in 2013-2016 compared with 2009-2012 fell 60.94%..The epidemic intensity of rabies in Guangxi was declining,and the prevalence of rabies was significantly decreased(?2 = 92.737,p <0.001).The cases of rabies in Yulin,Liuzhou,Chongzuo city dramatically dropped.From the crowd distribution,the proportion of male and female cases was 2.61:1,the main parts of cases included scattered and childcare7 children and farmers.3.The epidemiological characteristics of the injured crowed by animals and Post-exposure treatment in clinics of Qinzhou,Fangchenggang City in 2016.From time distribution,the incidence of rabies was high in summer and autumn,the main parts of cases included scattered and childcare children and farmers,and men were much higher than female,the main lower extremity of the injury is the lower limbs,and the second is the hand,which is consistent with the pathogenesis of rabies.The intensity of the vaccination in Fangchenggang City was higher than that in Qinzhou City in2016(?2 = 33.06,P <0.05).4.Analyses on the prevention and control effect of rabies in Guangxi province.The study of epidemiological ecology in the city of Guigang,Yulin and Chongzuo shows that after the disposure cost of rabies exposure was included in the new rural cooperative medical system in 2013,the reimbursement amount of rabies,the number of outpatient in rabies clinic and the rabies vaccine use have risen significantly,in which the vaccine use rate and the passive preparation use rate in Chongzuo is much higher than that in Guigang and Yulin(?2=12.45,P <0.05;?2=8.67,P <0.05),it is relevant to the incidence rate of rabies(r=0.624,P <0.05).During the past 11 years,the immunological density of dogs in Chongzuo is 92.56%,and 66.56% and 65.39%,respectively,in Qinzhou and Guigang.The immunological density of dogs in Chongzuo has significant statistical difference from that in other cities(?2=178.32,P <0.05).5.Relevant factors of rabies.In this study,the incidence rate and related factors of rabies in Guigang,Yulin and Chongzuo from 2009 to 2016 have been analyzed.Rabies is significantly related to the factors of the use of rabies vaccine and the immunological density of dogs,and represents negative8 correlation to the incidence of rabies.Conclusion1.From 2006 to 2016,the incidence rate of rabies in Guangxi has dropped from 1.114 / 100,000 to 0.117 / 100,000.In particular,the incidence rate of rabies was significantly reduced and the rabies epidemic area was also significantly contracted before rabies vaccine was included in the new rural cooperative medical system.The incidence of rabies is obviously seasonal,mainly in summer and autumn.Every year,the incidence peak happens from July to October.The high-risk occupational groups of rabies are scattered children and young adults,in which men owns higher potential than women.2.According to the data provided by the Ministry of Livestock and Fisheries,the immunization rate of dogs in Guangxi has gradually reached or close to 70%immunological barrier.Improving the level of immunization in dogs is the basic measure to prevent rabies,and it can effectively curb the interpersonal prevalence of rabies in Guangxi.3.The use of rabies vaccine and the immunological density of dogs are negatively correlated with the incidence rate of rabies.4.Combined with the results of this study and the actual situation in Guangxi,following prevention and control strategies are proposes:(1)strengthen the dog management,improve the immunization rate of dogs;(2)improve the timely disposure rate and immunization level after the exposure of rabies;(3)complete the mechanism of joint control and prevention,suggest that Guangxi establish a joint conference of rabies control and prevention,strengthen the information communication mechanism,improve the level of prevention and control of various departments,and constantly make the joint control and prevention mechanism efficient and long-lasting.