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Clinical Analysis Of The Relationship Between OSAHS (Obstructive Sleep Apnea Hypopnea Syndrome) And TIA (Transient Ischemic Attack) In Posterior Circulation

Posted on:2018-04-12Degree:MasterType:Thesis
Country:ChinaCandidate:M R T G L T Y E ZuFull Text:PDF
GTID:2334330515986199Subject:Neurology
Abstract/Summary:PDF Full Text Request
Objective: To analyze respectively the risk of OSAHS in different stages to TIA in posterior circulation and pathological mechanism between two disease.In order to provide clinical evidence for individual-based treatment also reduce the risk to stroke so that prevent from processing to vicious circulation.Methods: According to patients' symptoms and signs,we sequentially enrolled 30 posterior circulation TIA patients as the case group who were admitted in neurology department of the hospital.At the same time,we chose 34 patients as control group who were admitted for general check-up and had PSG results.Basic clinical features of all patients were recorded and analyzed using control study,and PSG results were compared between two groups.Then analyzed the correlation between OSAHS and posterior circulation TIA by applying Logistic regression test.Results: The number of OSAHS of case group was 24,control group was 18,P=0.035,there was statistic difference(p<0.05)between two groups.Severe OSAHS in case group was 11,which were rather higher than control group(2),P=0.04,the difference between two groups was statistically significant.Logistic regression test analyzed the correlation between posterior circulation TIA and all risk factors including OSAHS.The result revealed that LDL and diabetes were significant risk factors of TIA in posterior circulation.Between OSAHS and posterior circulation TIA,OR=0.538,P=0.702,there was no statistic independent relationship.Spearman test results showed,OSAHS has significant relationship with smoking,hypertension,LDL,Hcy and BMI.(P<0.05).Conclusion: 1.The incidence of OSAHS among the posterior circulation TIA patients is 80%.2.OSAHS is the one of the risk factors of the TIA in posterior circulation,but not the independent risk factor.3.OSAHS is related to smoking,hypertension,Hcy and BMI So that increase the risk of TIA in posterior circulation.
Keywords/Search Tags:OSAHS(obstructive sleep apnea-hypopnea syndrome), TIA(transient ischemic attack), Posterior circulation ischemia, Hcy(homocysteine), atherosclerosis
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