| Objective The knee joint is an important joint of the lower limb movement of the human body.Its stability and movement are basically controlled by the ligament.The anterior cruciate ligament(ACL)plays an important role in maintaining the stability and movement of the knee joint.Anterior cruciate ligament injury can lead to instability of the knee,severe and even lead to the occurrence of knee osteoarthritis.So arthroscopic damage to the anterior cruciate ligament reconstruction is essential.However,the choice of grafts,the more types,mainly autologous tendon,allogeneic tendon,artificial ligament,tissue engineering ligament,etc.,different grafts have their advantages and disadvantages.At present,the clinical use of the first two,limited by the source of autologous tendon less,allogeneic tendon may be rejection and other shortcomings,many clinicians use autologous tendon and allogeneic tendon joint weaving as a graft reconstruction Anterior cruciate ligament,related histological studies have shown that auto/allo-graft reconstruction of ACL is conducive to promoting the graft healing process.However,there are relatively few studies on the related biomechanical properties of the grafts after the application of the auto/allo-graft.Therefore,this article explores the biomechanical changes of the anterior cruciate ligament after reconstitution of the anterior cruciate ligament by the animal experiment,and compared with the biomechanical changes of the anterior cruciate ligament reconstruction with allogeneic tendon to clarify the auto/allo-graft and allogeneic graft.The differences in the biomechanical properties of tendon reconstruction.Methods Healthy adult New Zealand rabbits 40(Wuxi City Schistosomiasis Prevention Center),weight(3 ± 0.30)kg,male and female 20.Rabbits were randomly divided into two groups: auto/allo-graft tendon group(mixed group)and allogeneic tendon group(allogeneic group).40 rabbits were normal,the knee before the drawer check and the Lachman test were negative.There were 4 time nodes(3,8,12,24 weeks postoperatively)and 5 samples per time node.The extensor digitorum longi(EDL)at the ankle joint of the bilateral hind limbs was reconstructed as a reconstructed ACL.The mixed group was reconstructed with autologous tendon and allograft tendon,and the ACL was reconstructed by allogeneic tendon.Five rabbits in each group were sacrificed at 3,8,12 and 24 weeks after operation.The tibia and femur were cut off at 4 cm from the knee.All soft tissue around the knee was removed,only the graft was preserved,and the cement And the tibial ends were prepared into a femur-graft-tibial complex,placed on the fixture of the electronic universal testing machine Instron E10000(provided by the Mechanical Laboratory of the Suzhou University Institute of Orthopedics).The bone tunnel was adjusted in the same direction as the tensile force,Test and statistical analysis of experimental data.Results At the time of 3,8,12 and 24 weeks postoperatively,the ultimate load and stiffness of the mixed group were higher than those of the allogeneic group(P <0.05).The tensile length of the mixed group was lower than that of the allogeneic group(P <0.05)The difference between the two groups was statistically significant.At the postoperative level of 3 and 8 weeks,the grafts were removed from the bone tunnel.There was no significant difference in Fisher exact test at 4 time nodes(P> 0.05).Conclusion Reconstruction of ACL,The biomechanical properties of the auto/allograft is better than allogeneic tendon.The changes in the biomechanical properties of the tendon and allograft tendon are similar to those of the allogeneic tendon and allogeneic tendon.The trends of the limit load and the stiffness are all from the strong to the weak and the gradual enhancement process.To provide appropriate theoretical support for the clinical selection of the auto/allo-graft as an implant... |
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