objective to further evaluate the Baofei ningsou granule in the treatment of chronic obstructive pulmonary disease(COPD)efficacy and safety of lung heat phlegm and blood stasis type.Methods: 72 cases were selected according to the test conditions.The patients were randomly divided into two groups,and the patients were discharged from the trial because of the compliance of the patients,and finally dropped out in 12 cases,and the effective rate was in the treatment of 60 cases.Among them,Baofei ningsou particles 30 cases of test group and control group of 30 cases of acute bronchitis syrup.Test group: oral Baofei ningsou particles,each bag of 15 g,boiling water 100 ml blunt,3 times a day;the control group: oral Jizhi syrup,a daily dose of 90 ml,3 times a day,each time 30 ml.The course of treatment was 2 weeks.Observe and record the two groups of patients after treatment,cough,asthma,chest tightness,shortness of breath,sputum color traits and other therapeutic effects,and the ratio of system analysis.Results: the main symptoms of traditional Chinese medicine single degree of two groups of patients after treatment by rank sum test contrast: cough and asthma(Z=-2.095,P=0.036),dyspnea(Z=-2.036,P=0.042),sputum color traits(Z=-2.059,P=0.036),fever(Z=-2.583,P=0.01),(Z =-2.752,P=0.006 mouth dry mouth),P values were less than 0.05,there are significant differences,with statistical significance.The treatment group before and after treatment of single TCM main symptoms by rank test contrast: cough and asthma(Z=-9.414,P < 0.01),dyspnea(Z=-4.472,P < 0.01,sputum color traits(Z=-6.789,P < 0.01),fever(Z=-2.270,P=0.023),bitter taste and dry throat(Z=-7.402,P < 0.01),in addition to the symptoms of fever P value equal to0.023 is greater than 0.01,the P values were less than 0.01,with significant differences,with statistical significance.Comparison of two groups of patients with comprehensive curative effect: the treatment group 0 cases were cured,7 cases markedly effective,21 cases effective,2 cases ineffective,the total efficiency of 93.33%;control group 0 cases were cured,2 cases were cured,18 cases effective,10 cases ineffective,the total efficiency of 66.67%,the comprehensive effect of the treatment group as the control group,and the rank a contrast test(Z=-2.834,P=0.005),the P value is 0.005 less than 0.01 had significant differences,with statistical significance.Conclusion: Baofei ningsou granule can improve the syndromes of traditional Chinese medicine for the treatment of chronic obstructive pulmonary disease exactly. |