Clinical Observation On The Efficacy Of Treatment Of Advanced Esophageal Catcinoma With The Method Of Eliminating Sputum To Relief Depression Combined With TP Chemotherapy

Objective:Clinical observation on the efficancy of treatment of advanced esophageal cancinoma with the method of eliminating sputum to relief depression combined with TP chemotherapy.Methods:80 cases of advanced Cross resistance of tan and qi type in patients with esophageal squamous cell carcinoma,the patients were rand-omly divided into treatment group and control group with 40 cases in each group.The treatment group took treated with the method of eliminating sputum to relief depression combined with TP chemotherapy,while the control group was treated with TP chemotherapy alone.The 2 cycles were observed continuously.Before treatment and after treatment for two cycles of each evaluation of 1 times,a total of 2 times.The treatment group and control group before and after treatment in patients with tumor size,serum tumor markers,KPS score,TCM syndrome,adverse reactions and other indicators and the use of statistical evaluation.Results:1.In the evaluation of tumor size,the remission rate of the treatment group was higher than that of the control group,but there was no significant difference between the two groups(P>0.05).2.Treatment group and control group before and after treatment for 2 weeks after the serum tumor markers CEA,SCC concentration,the treatment group was better than the control group,there was a significant difference(P<0.05).3.In the KPS score,the treatment group and the control group after treatment were higher than before treatment,there was a significant difference(P<0.05),and the treatment group KPS score was significantly higher than the control group,there was significant difference(P<0.05).4.In the score of TCM syndromes,the treatment group decreased after treatment than before treatment,there was statistical difference(P<0.05);The control group before and after treatment,there is no statistical difference(P>0.05).5.In the side effects,the treatment group and the control group,compared with the control group,the incidence of neutrophil,nausea and vomiting were significantly reduced,there was a significant difference(P<0.05).Conclusion:1.The method of resolving phlegm and removing depression has the effect of stabilizing the size of tumor.2.The method of resolving phlegm and removing depression with TP regimen can reduce the Cross resistance of tan and qi in patients with advanced esophageal cancer of serum tumor markers.3.The method of resolving phlegm and removing depression can enhance Karnofsky score,improve the clinical symptoms,and improve the quality of life of patients.4.The method of resolving phlegm and removing depression can alleviate the incidence of myelosuppression and nausea and vomiting caused by chemotherapy.