A Clinical Study On Correlation Between Microembolic Signal And Middle Cerebral Artery Stenosis

Objective:To investigate the relationship between microembolic signal(MES)and middle cerebral artery(MCA)stenosis based on transcranial Doppler and imaging.Methods:70 patients with symptomatic MCA stenosis and 20 patients with asymptomatic MCA stenosis were selected.The symptomatic MCA stenosis group included 14 patients with transient ischemic attack(TIA)and 56 patients with cerebral infarction.All the patients in our study received magnetic resonance images to detect the cerebral infarction and their location.All the patients were examined by magnetic resonance angiography,computed tomography angiography or digital subtraction angiography.The degrees of the MCA stenosis were graded.Microembolic signals of MCA were monitored by transcranial Doppler sonography.Results:The positive rates of the MES in patients with symptomatic MCA stenosis were higher than those in asymptomatic MCA stenosis group 30.0%(21/70)vs.5.00%(1/20),P<0.05.The positive rates of MES with light MCA stenosis,moderate MCA stenosis and severe MCA stenosis were significantly different 0%(0/10)vs.31.57%(6/19)vs.40.0%(14/35),P<0.05.The NIHSS Scores of patients with positive MES in symptomatic MCA stenosis were lower than those in patients with negative MES(P<0.05).The positive rates of MES with border zone infraction and scattered cortical infarction in symptomatic MCA stenosis group were higher than those in other subtype of cerebral infarction(P<0.05)Conclusions:There are differences between the positive rates of MES in symptomatic MCA stenosis grop and asymptomatic MCA stenosis group.The positive of MES and cerebral ischemic events are highly correlated.Different types of cerebral infarction should receive individual treatment with adequate assessment cerebrovascular imaging and MES monitoring.