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Study On Preparation Technology And Quality Standard Of “Fu Ling Pian”

Posted on:2018-06-20Degree:MasterType:Thesis
Country:ChinaCandidate:H GaoFull Text:PDF
GTID:2334330512496854Subject:Pharmacy
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With the changes in the living environment,living standards and life styles,and advances in medicine,the disease spectrum has undergone significant changes.General infectious diseases are gradually being controlled,and malignancy is becoming increasingly common and seriously threatening human life and quality of life One of the major diseases.At present,common treatment methods are drugs and chemotherapy,and this treatment means to kill cancer cells at the same time,the body's immune system will cause damage,the body's immune capacity will decline sharply.This project makes full use of the rich biological resources of the Dabie Mountains,and develops the research on the development of nutritious food with Poria,Ganoderma lucidum and turmeric as the main raw material.It will change the traditional method of treating malignant tumor and enhance the immune function of the human body by regulating the immune factor Function,in order to achieve the purpose of cancer prevention and treatment.This paper includes the following aspects: 1?Poria determination and methodological research.Poria is one of the main raw materials in the "Fu Ling Pian".The polysaccharides and total triterpenes contained in the Chinese Pharmacopoeia are the main active ingredients.The content of Poria in Chinese Pharmacopoeia is not determined by colorimetric method.Of the polysaccharide and total triterpenoid content and completed its methodological research.2 ? "Fu Ling Pian" preparation process research,developed a medicine extraction methods,preparation molding processresearch and so on.Poria,Ganoderma lucidum contains alcohol-soluble triterpenoids and water-soluble polysaccharides,turmeric contains alcohol curcumin and water-soluble active ingredients,design extraction,extraction method,first with a certain concentration of ethanol extraction,dregs and then water extraction.The The factors influencing the extraction of ethanol were as follows: ethanol concentration,alcohol content,extraction times and extraction time.Four factors were used to study the effects of ethanol on the extraction of ergosterol and curcumin in turmeric.The regression analysis showed that the best Extract parameters.The factors affecting the extraction of decoction were water supply,extraction times,extraction time,design three factors three levels of orthogonal design test,the total polysaccharide as an index,through the variance analysis,get the best extraction parameters.The preparation of the tablets was carried out,and the preparation of the tablets was carried out to prepare the formulations to meet the standards.3?Quality standards,the goods in Poria,Ganoderma lucidum contains functional polysaccharides,the establishment of the total content of polysaccharides determination,and the methodology was investigated.Turmeric content of curcumin,the establishment of curcumin content determination items,and the methodology of the study.Qualitative identification of Ganoderma lucidum.4?The stability of the preparation was determined by examining the shape and appearance of the product,the examination items,the microbiological limits,the contaminants,the qualitative identification and the content determination.Room temperature inspection for 3 months,accelerated study for three months.According to health food requirements to establish the quality standards of this product.
Keywords/Search Tags:Fu Ling Pian, preparation process, quality control
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