The Clinical Study Of Hashimoto's Thyroiditis With Transient Thyrotoxicosis

Objective: This study used a retrospective analysis method,selection of clinically diagnosed Hashimoto transient thyrotoxicosis and Hashimoto's hyperthyroidism cases were the 32 cases as the research object,a comparative study of Hashimoto of thyrotoxicosis and Hashimoto's hyperthyroidism in the pathogenesis,clinical symptoms,signs and laboratory examination of the similarities and differences between the room,and analysis of the use of compound elimination treatment of hyperthyroidism,gall Fufangjiakang tablets in the treatment of Hashimoto a transient thyrotoxicosis,the identification and treatment of this disease was discussed,in order to provide a new understanding of the diagnosis and treatment of this disease.Methods: A total of 32 patients(A group)who were diagnosed with Hashimoto's transient thyrotoxicosis in Hubei Provincial Traditional Chinese Medical Hospital were enrolled in this study.The patients were diagnosed as Hashimoto's thyroiditis(Group)and the patients were diagnosed as Hashimoto's thyroiditis(B group).A,B two groups of patients with age,sex,clinical symptoms,the degree of goiter,texture,serum FT3,FT4,TSH,FT3/FT4,TGAb,TPOAb,TRAb test results and complications.To study and analyze thedifferences of clinical symptoms and laboratory indexes of the patients treated with compound Chinese medicine for removing goiter and hyperthyroidism tablets.Results: 1.The age of onset of the disease in the group was between 18-50 years old,and were higher in female,the age and sex ratio of the two groups had no significant difference(P>0.05).2.Bridges in the past group of symptoms of traditional Chinese medicine syndrome score,heart rate were lower than the Hashimoto hyperthyroidism group(P<0.05),indicating that the incidence of clinical symptoms of mild.3.Among the two groups with different levels of goiter proportion had significant difference(P<0.05),Hashimoto had a sepsis group with less than 1 degree enlargement accounted for the most.4.There was no significant difference between the two groups(P>0.05),and the proportion of the two groups was not statistically significant(P>0.05).5.There was significant difference between the two groups in the proportion of the increase of serum FT3(P<0.05),the proportion of FT4 increased in the two groups was statistically significant(P<0.05).The FT3 group and FT4 group were the most frequently seen in the patients with transient toxicity.There was no significant difference in the level of TSH(P>0.05).The FT3/FT4 value of the transient toxic group was lower than that of Hashimoto's hyperthyroidism group,and the difference was statistically significant(P<0.05).6.There was significant difference in TGAb,TPOAb negative,positive and strong positive rate between the two groups(P<0.01),and the level of the antibody positive in the patients with transient toxic disease was lower than that in the control group.There was no significant difference in the positive rate of single and double antibody(P>0.05).7.The TRAb negative rate was significantly higher in Hashimoto's disease group(96.9%),and the difference was statistically significant(P<0.01).8.There was no complication(75%),and the difference was statistically significant(P<0.01).9.Transient Thyrotoxicosis 's group accounted for the highest proportion(65.6%)in the month of 1-3(P<0.01),and the proportion of recovery in 6 month was significantly higher than that in the group of Hashimoto's thyroiditis,the difference was statistically significant(P<0.01).10.FFXYJK tablets,FFJK tablets before and after the treatment of TCM symptoms score,the laboratory indicators of the overall differences were statistically significant(P<0.05).11.Transient Thyrotoxicosis 's group in the treatment of a group of patients with hyperthyroidism after a faster recovery,generally can be restored within 1 courses,2 courses of stable condition.After 2 courses of consolidation treatment,the cure rate of the two groups were significantly higher than those of the 1 courses.Conclusion: 1.Hashimoto's transient thyrotoxicosis is generally in the middle and elder age,and the proportion of female is more than that of the male.2.The clinical symptoms and signs of hyperthyroidism were mild.The degree of goiter have significance in the differential diagnosis of this disease,the general performance is less than 1 degree of goiter.There is no significant difference between the thyroid gland and the Hashimoto's disease in the thyroid gland.The thyroid texture or texture is only used as a reference for identification.3.The thyroid function of the disease FT3,FT4 slightly increased,FT3/FT4 ratio is low,and there are both normal subclinical hyperthyroidism,can be used as the basis for the diagnosis of this disease,the level of TSH can not be used as a diagnostic basis.4.The positive rate of TGAb and TPOAb was lower than that of Hashimoto's disease,and the positive effect of single and double antibody was not significant for clinical diagnosis.5.TRAb negative can be used as the basis for the diagnosis of this disease,but there are also individual(3.1%)suspicious positive results.6.There is no common complication of hyperthyroidism in clinical disease,but it's necessary to treat after have it.7.Its Thyrotoxicosis is also transient.The time of thyrotoxicosis is no more than 3 months after treating,the clinical symptoms were also significantly reduced within 3 months.8.The use of FFXYJK tablets for the treatment of patients with hyperthyroidism,the treatment of FFJK tablets,the specific dose according to the principle of individualization,after the initial treatment should be closely monitored thyroid function,timely adjustment of dose.9.After diagnosis treatment should pay attention to the follow-up,if a large fluctuations in power,when necessary,stillneed to perform FNAC pathological examination confirmed.