The Correlation Study Btween Lesion Zoning Of High Grade Cervical Intraepithelial Neoplasia With Five Viscera Syndrome Elements Based On Colposcopic Imaging

Objective:Using syndrome differentiation,with high grade cervical intraepithelial neoplasia(HSIL)were selected as the research object,for the four diagnostic information collection to the research object,and the application of colposcopy and pathological imaging technology,determine the HSIL coordinates of the cervical lesions in.To investigate the distribution characteristics of HSIL TCM syndrome and the correlation between HSIL cervical lesions and the syndrome of Five viscera syndrome.Methods:The cases were collected from January 2016 to January 2017 in the Hospital,the pathological examination confirmed HSIL.All cases were four diagnostic information of TCM syndromes questiorinaire according to the CIN reference collection,"Zhu Wenfeng syndrome" of TCM syndrome differentiation principle.Analysis of colposcopy and histopathology in all cases,the construction of colposcopy in traditional Chinese medicine inspection coordinates,to determine the coordinates of the cervical lesions in HSIL.To investigate the distribution characteristics of TCM Syndromes of HSIL,and the correlation between the distribution of cervical lesions and the syndrome elements of Five viscera.Result:1.The subjects in the collection of 93 cases of HSIL patients,age:30-49 years old most,65 people(69.9%),60-69 years old at least,4 people(4.30%);BMI index:18.4-23.9 up,66 people(70.97%);Occupation:staff up to 34 people,(36.56%),followed by the unemployed,26 people(27.96%);contraception:the use of IUD,no fixed contraception most,23 people(24.73%);the first sex:more than 20 years at most,38people(40.86%);pregnancy:3 times and above the most,47 people(50.54%).2.High level CIN TCM syndrome distribution characteristics:? Disease essence syndrome factor distribution:wet most,61 cases(65.59%),followed by heat,yin deficiency,Yang deficiency,blood stasis.?Disease location syndrome factor distribution:the uterus most,38 cases(40.86%),followed by liver,spleen,kidney,heart,abdomen.? TCM syndrome types distribution:liver dampness heat syndrome,23 cases(24.73%),followed by kidney yin deficiency and dampness syndrome,spleen deficiency syndrome,liver yin deficiency,spleen dampness heat syndrome,damp heat syndrome,kidney yang deficiency of uterus.?The five zang organs of the disease:33 cases(37.50%),followed by spleen in 28 cases(31.82%),kidney in 24 cases(27.27%),heart in 3 cases,anyone in patients with lung disease.3.Cervical lesions in HSIL patients:Coordinate inspection of cervical lesions distribution:026 visible cervical lesions 37 coordinate in the first round of the eleventh quadrant,16 cases(18.18%),followed by cervical canal in 15 cases(17.04%),the first round of the seven quadrant in 13 cases(14.77%);43 cases of patients with lesions involving multiple coordinates;? The four quadrant cervical lesions:lesions were visible distribution area,left upper quadrant of the most,24 cases(27.27%),followed by the lower right quadrant,right upper quadrant,left lower quadrant,12 cases of patients with lesions involving more than one quadrant;? Rounds of cervical lesions distribution:lesions confined to the first round of the most,51 cases(57.95%),followed by is confined to the cervical canal,confined to the second round,26 cases of patients with lesions involving two or more.4.Correlation between HSIL cervical lesions and the syndrome of Five viscera syndrome:? Coordinate inspection cervical lesions and disease:Five Viscera disease syndrome factor was statistically significant in 37 coordinate distribution(P=0.002).Liver involvement in the seventh quadrant of the first round,Splenic lesions in the eleventh quadrant of the first round,Nephropathy in the cervix,coordinate distribution and other viscera syndromes are different(coordinate distribution and other viscera syndromes are different(a?0.008);? The "four quadrant cervical lesions and viscera disease:there was a significant distribution of five viscera syndrome factor in the four quadrant(P=0.000121);? The hepatic lesions in the upper left quadrant,the change in the right upper quadrant,nephropathy in the cervix,quadrant distribution and other dirty syndromes are different(coordinate distribution and other viscera syndromes are different(a<0.005);? Rounds of cervical lesions and viscera disease:five syndrome elements of disease location round number distribution was statistically significant(P=0.008).Liver lesions involving the 2 round and above,splenic lesions confined to the first round,renal lesions confined to the cervical canal,there are differences in the distribution of the number of rounds and other dirty cards(??0.005).Conclusion:1.HSIL is often occurs in the age of active sexual life,sexual behavior,premature sexual life,and the number of pregnancy are the high risk factors of HSIL.2.Wet is the basic disease syndrome HSIL,heat,yin deficiency and yang deficiency,blood stasis and clip for pathogenic factors;HSIL viscera disease syndrome factor of liver,spleen,kidney,heart and liver;damp heat syndrome is the most common HSIL syndrome,spleen deficiency,kidney yin deficiency and dampness syndrome.3.HSIL cervical lesions can be a single lesion,can also be multiple lesions,multiple lesions can accumulate multiple coordinates.The pathological changes of HSIL can be clustered in a certain quadrant,a round or acertain region.4.HSIL partition and viscera syndrome of cervical lesions,lesions of the coordinates,quadrant,round number can be used for HSIL inspection.The lesions were located in the first round of the seven quadrant/lesion in the left upper quadrant/lesions involving two rounds and above and the disease of the liver;the lesions were located in the first round of the eleventh quadrant/lesions in the right upper quadrant/limited to the first round with the syndrome factor in the spleen;the lesions located in the cervical canal and disease in the kidney.