Application Value About Dynamic Enhanced MRI In Cervical Lymphadenopathy

Objective To evaluate the role of dynamic contrast-enhanced MR imaging(DCE-MRI) in cervical lymphadenopathy.Methods Thirty four cases of cervical lymphadenopathy were selected and examined by conventional 3.0 T MRI.The pattern of time-signal intensity curve (TIC) at the region of interest (ROI) positive enhancement integral(PEI),time to peak (TTP), maximum slope increase (MSI), etc, were achieved using post-processing software. And all the lesions were evaluated by dynamic contrast-enhanced MR imaging.Results The distribution types of TIC in 45 patients were as follows. For the benign lesions type I had 8 cases, type II 3 cases, type III 2 cases while for malignant lesions type I was seen in 3case, type II in 5 case, type III in 13 cases. Statistically significant differences in the distribution types of TIC existed between benign and malignant lesions. Taking type II and type III as the criterion to differentiate the benign lesion from the malignant one,the sensitivity, specificity and accuracy of TIC for the diagnosis of malignant lesions were 85.7%, 61.5% and 70.6% respectively.Taking type III as the criterion to differentiate the benign lesion from the malignant one, the sensitivity, specificity and accuracy of TIC for the diagnosis of malignant lesions were 62.0%,84.6% and 70.6% respectively.But Perfusion parameter were no significant difference in terms of statistics.Conclusion Dynamic contrast-enhanced MR imaging has certain value in differential diagnosis of benign and malignant lymph node lesions.