Analysis Of Clinicopathological And Imaging In 100 Patients With Orbital Tumors

Purpose To generalize the histopathologic classification and distribution of 100 orbital tumors,to investigate the CT \MRI \PET-CT imaging characteristics,to study the distribution in orbital division of orbital neoplasm,so it can improve the diagnosis of orbital tumors and provide imaging basis of preoperative surgical approach.Methods A retrospective review of 100 patients with orbital tumors identified by pathological examination at the Union Hospital,Huazhong University of Science and Technology from February 1,2013 to December 30.2015.According to internationally accepted Shield pathological classification,the distribution of pathoology and common tumors in different age groups are summarized.The different clinical features and disrtibution in benign and malignant orbital tumors are analyzed.Generalize CT\MRI \PET-CT imaging characteristics in order to improve the diagnosis of orbital tumors and provide imaging basis of preoperative surgical approach. The different CT imaging characteristics in benign and malignant orbital tumors are analyzed.Results In this study,the most common orbital tumors in general category are vasculogenic(41%),among which the cavernous hemangioma occupied 34 cases.76%of benign and malignant tumors was 24%.Among benign tumors, the most common are vasculogenic(53.95%),while the second and third are neurogenic lesions(11.84%)and cystic lesions(10.53%).The most common tumor is malignant lymphoma,accounting for 37.5% of all malignant tumors and 9% of all orbital tumors.Among children, hemangioma(35.71%) and cystic lesions(21.43%) are ranked first,while among older,the most common tumor is malignant lymphoma(13.33%).Exophthalmos in benign tumors are 37 cases and 18 cases in malignant tumors,there are significant differences(P<0.05) between the two.Bone destruction in benign tumors are 18 cases and 11 cases in malignant tumors,there are significant differences(P<0.05)between the two.Extraocular muscle swelling in benign tumors are 16 cases and 12 cases in malignant tumors,there are significant differences(P<0.05)between the two.Conclusions In this study,the most common orbital tumors in general category are vasculogenic, among which the cavernous hemangioma is ranked first.Hemangiomas and cystic lesions are the most common in children while Hemangiomas in adults and malignant lymphomas in olders.The ratio of benign and malignant tumors is 3:1.The ratio of exophthalmos in malignant tumors are higher than that of in benign tumors;the CT imaging characteristics in 74 benign tumors and23 malignant tumors are compared.It is studied that the ratio of bone destruction and extraocular muscle swelling in malignant tumors is higher than that of in benign tumors.CT imaging features of the optic nerve thickening, calcification, intratumoral cystic show no significant statistical difference between benign and malignant tumors.The CT and MRI imaging characteristics in orbital tumors have unique advantages in the diagnosis and preoperative localization of the disease, while PET-CT as a new method of examination,it has significant value in identification of malignant tumors, disease recurrence,metastasis, and evaluation of the efficacy.