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Clinicai Value Of The Application Of 128-Slice Spiral CT Angiography In The Diagnosis Of Supra-Aortic Arteries Stenosis

Posted on:2017-12-11Degree:MasterType:Thesis
Country:ChinaCandidate:L ZhangFull Text:PDF
GTID:2334330503986431Subject:Imaging Medicine and Nuclear Medicine
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Objective:Compared with digital subtract angiography results,evaluation of the reliability of the supra-aortic arteries stenosal degree and complicated aneurysms with 128-silce spiral computed tomography angiography. We evaluate the clinical valve of CTA in the diagnosis and limitation of ischemic cerebrovascular disease.Methods:Compile 44(29male,15female)borderline cases with supra-aortic arteries stenosal between February 2014 and April 2015 in department of internal medicine of our hospital,whith had undergone supra-aortic arteries computed tomography angiography examination and digital subtract angiography examination within ten days.CTA was performed on a Siemens 128-slice spiral CT scan machine.The image post-processing techniques were used to detect and analyze the vascular stenosis.Two senior radiologists to evaluate the degree of stenosis of arterial blood vessels in a blind ways.Common image post-processing method: VR?MPR?CPR ?MIP?SSD and others.The atherosclerotic plaques were grouped as calcified plaque?mixed plaque and vulnerable plaque on CTA images.With the results of DSA as the gold standard to compare the results of CTA with that of DSA.The internal and external vascular stenosis and complicated aneurysms were statistical analysis.The sensitivity,specifility,positive predictive value,negative predictive value of CTA were analysed.compared with DSA.Results:The CTA readings correlated with DSA findings in 935 vessels(96.5 %),Sensitivity of 128-sile CTA in diagnosis supra-aortic arteries is 93.6%, specificity is 99.3%,PPV is 97.4%, NPV is 98.3%. Consistency test of the Kappa is 0.9172. 38 calcified plaques?41 mixed plaques and 76 vulnerable plaques were detected on CTA.The sensitivity and specificity of CTA in the diagnosis of intracranial aneurysm were 100%.Conclusion: 128-silce spiral CTA is a noninvasive or minimally invasive inspection,which has a high sensitivity and specificity in the diagnosis of supra-aortic artery stenosis and aneurysm.CTA can also clearly observe and evaluate the properties of atherosclerotic plaque.To some extent,CTA replaces DSA can be used for preoperative diagnisis ? post-operative evaluation and epidemiological investigation of supra-aortic arteries stenosis disease.
Keywords/Search Tags:CTA, DSA, supra-aortic arteries stenosis, atherosclerotic plaque, aneurysm
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