The Intervention Effect On Bu Shen He Mai Particles For Homocysteine Levels Of The Elderly H Isolated Systolic Hypertension

Objective:Bu Shen He Mai Particles on level 1, level 2 old H isolated systolic blood pressure of hypertension success rate and the clinical curative effect and security of the homocysteine levels research, for the treatment of traditional Chinese medicine with high homocysteine levels, provide the evidence base in senile patients with simple systolic hypertension. Methods: Will be diagnosed with H isolated systolic hypertension in the elderly patients in 70 cases, in accordance with the principle of simple randomized, controlled, divided into treatment group and the control group(n = 35). Both groups of oral maleic acid enalaprilat and folic acid pills, the treatment group take a Bu Shen He Mai Particle preparation, control group given a placebo. Respectively on two groups of patients' blood pressure, Hcy levels and the TCM syndrome were observed and compared. Finally USES SPSS17.0 statistical software for data analysis, draw the conclusion. Results: 1.After treatment of conventional western medicine combined Bu Shen He Mai Particles with conventional western medicine combined the placebo group are significantly lower blood pressure than before treatment, significant difference(P < 0.01), the conventional western medicine combined Bu Shen He Mai Particle group have more advantages in the placebo group(P < 0.01);2.Routine western medicine combined Bu Shen He Mai Particle group after treatment with conventional western medicine combined placebo Hcy levels were significantly lower, very significant difference(P < 0.01), And conventional western medicine combined Bu Shen He Mai Particles of arteries and veins of lowering Hcy more significantly(P < 0.01);3. After treatment, two groups of clinical symptoms were improved. But the conventional western medicine combined Bu Shen He Mai Particle group has improved significantly in the placebo group(P < 0.01);4. Safety evaluation, in the process of treatment, two groups of patients did not appear any discomfort, before and after treatment the blood, urine, stool and liver and kidney function not seen obvious difference. Conclusion:Conventional western medicine combined Bu Shen He Mai Particle group with routine western medicine combined placebo and Hcy blood pressure before treatment were significantly lower, but the conventional western medicine combined Bu Shen He Mai Particle group has more advantages. Bu Shen He Mai Particles significantly lower blood pressure, and the function of Hcy. Clinical symptoms were improved in both groups, but western medicine combined Bu Shen He Mai Particle group effect is more obvious. To sum up, Bu Shen He Mai Particles for the treatment of elderly H isolated systolic hypertension and kidney deficiency syndrome of effective prescription, at the same time, without any adverse reaction in clinical observation, can be widely used in clinical.