Evaluation Of Left Ventricular Systolic Function In Patients With Coronary Heart Disease Associated With Depression By Real-time Three-dimensional Echocardiography

Objective:To investigate the changes of left ventricular systolic function in patients with coronary atherosclerotic heart disease (heart disease coronary, CHD) associated with depression by real-time three-dimensional echocardiography.Materials and methods:From October 2013 to April 2014,100 patients with coronary heart disease diagnosed by coronary angiography in the Department of Cardiology of Zhongda Hospital Affiliated to Southeast University were selected. Among them,45 cases had single vessel disease,34 cases with double branches and three cases with 21 lesions. Of these,35 were allocated to the CHD-depression group (age 48-74 years, mean age 61.23±6.78 years) and 65 to the CHD-non-depression group (age 40-77 years, mean age 58.31±7.93 years) according to the Hamilton Depression Scale (HAMD), and 38 cases of normal subjects served as normal control group (age 40-70 years, mean age 56.76±6.73 years old). Application of real-time three-dimensional echocardiography cardiac patients with images of collection, selected the left ventricular end diastolic volume (Left ventricular end volume, LVEDV), left ventricular end systolic volume (Left ventricular selection of volume, LVESV) and left ventricular ejection fraction (LVEF) to analysis left ventricular systolic function. Using SPSS 14.0 statistical software for data processing, and using of single factor analysis to compared the variance between two multiple group, P<0.05 was statistically significant.Results:1. There was no significant difference in gender, age, body mass index and heart rate, among three groups. The CHD-depression group and the CHD-non-depression group showed no significant difference in the general data of gender, age, body mass index, heart rate, blood pressure and diabetes and so on.2. Real time three-dimensional ultrasound reconstruction was obtained for all the subjects.3. LVEF in the CHD-depression group (0.56±0.08) was lower compared with it in the normal group (0.62±0.05) and the CHD-non-depression group (0.60±0.05), and the difference is statistically significant (P<0.05); LVESV in the CHD-depression group (34.20±11.14ml) was higher compared with it in the normal group (28.23±6.23ml) and the CHD-non-depression group (31.33±8.16ml), and the difference has statistical significance (P<0.05); LVESV increases in the CHD-non-depression group compared with it in the normal group (31.33+8.16ml vs 28.23+6.23ml), but the differences hasn't statistical significance (P>0.05). The difference of LVEDV was not statistically significant (P>0.05) among the three groups (77.5+16.85ml vs 78.26+18.55ml vs 75.23+12.36ml).Conclusions:1. Left ventricular systolic function in patients with coronary heart disease associated with depression can be accurately evaluated by real-time three-dimensional echocardiography.2. Left ventricular systolic function in the CHD-depression group is lower compared with it in the CHD-non-depression group.