Clinical Application Of DTI In Cerebral Hemorrhage Corticospinal Tract Injury Research

Objective:To evaluate the relationship between the basal ganglia hemorrhage and corticospinal tract injury;To evaluate the di fferent effects between neuronavigation-assisted and the medical trea tment group.Methods:During March 2015 to January 2016,We collected 94 patients in Brain Hospital of First People's Hospital of Chenzho u Affiliated with Nanhua University admitted small amount(15-40 m l) basal ganglia hypertensive intracerebral hemorrhage hospitalized.A ccording to choice of treatment were divided into experimental grou p(neuronavigation-assisted treatment group, 47 cases) and control g roup(medical treatment group, 47 cases).Based on the integrity of t he corticospinal tract neuronavigation-assisted treatment group was d ivided into A1, A2 two subgroups: A1 group of 22 cases; A2 grou p of 25 cases.All patients within 48 hours after onset and 14 days Brian CT DTI scan and NIHSS scores were to give bilateral cortic ospinal tract(corticospinal tract, CST), anisotropy value(fractional anisotropy, FA), fiber tractography(diffusion tensor tractography, DT T), grading paralysis(paresis grading, PG).Using SPSS 19.0 statistic al software and independent samples T test was used for statistical analysis and comparison.Results:Through the analysis, comparison between the experime ntal group(neuronavigation-assisted treatment group) and control gro up(medical treatment group) and neuronavigation two subgroups co rrelation was found within 48 hours after the initial onset DTI ima ging showed that the experimental group and the control group the affected side of the cerebral peduncle and internal capsule FA value s were reduced, no significant difference(P> 0.05) groups.14 days after the onset of DTI imaging revealed that the experimental group FA values(internal capusar 0.49 ± 0.02, cerebral peduncle 0.47 ± 0.02) than the control group(internal capusar 0.39 ± 0.04, cerebral peduncle 0.42 ± 0.04) was significantly higher, the two groups ther e were significant differences(P <0.05),DTT from the experimental group show cortical spinal tract injury recovery better than the cont rol group.On the clinical manifestations, the experimental group(M G score 3.85 ± 1.16) muscle recovery better than the control group(PG score 5.01 ± 0.95), There were significant differences(P <0.05) groups.Neuronavigation A1 group after FA values(0.50 ± 0.02) i s higher than the A2 group(0.48 ± 0.02), the difference was statist ically significant(P <0.05).Conclusion:DTI can assessment the extent and scope of the CST injury very well in patients with cerebral hemorrhage;Neuronavigation-assisted treatment effect were better than the medical treatme nt for small to medium basal ganglia hemorrhage.