Study Of The Association Risk Factors Of Cervical Intraepithelial Neoplasia In Northern Shandong Area

Objective:Discuss the risk factors of cervical intraepithelial neoplasia. Screen the risk factors of CIN in northern Shandong area by epidemiological investigations to provide scientific proof for making preventive measures.Methods:Collect the information of 300 patients in case group and 300 patients in control group by epidemiological questionnaire and follow-up. All the relevant factors will be analysised by logistic regression.Results:The Independent risk factors of CIN are smoking, high-risk human papillomavirus infection, multiple sexual partners (wife & husband), intake of exogenous estrogens, and high risk men. Protective factors are HPV(-) and contraception by condom.Conclusions:The morbidity of CIN will raise when exposure to risk factors. Education campaign can make people be alert to CIN and reduce exposure to risk factors. The prevalence of CIN and cervical cancer will be reduced. Taking the focus of screening on the women who exposure to the risk factors can improve the detection rate of CIN.