| ObjectiveAnkylosing spondylitis is a kind of immune disease of the joints of the spine, the age of onset of 13-31 years old, the peak age at 20-30 years old, 40 years old and 8 years old before the disease is rare. Men are more common in women than in men and women. The ratio of male to female is (2-3):1. The prevalence rate of our country is about 0.26%. The disease is easy to be deformed and disabled, and the quality of life of patients with adverse effects. Because the disease is hidden, early symptoms are lighter, more performance for the lumbar sacral pain, clinical and more attention, the diagnosis of common pain in the waist, resulting in missed diagnosis, missed the best treatment period, to the diagnosis of ankylosing spondylitis, spine has been rigid deformation, small joint movement, then has been unable to recover. At present, ankylosing spondylitis drug treatment in the country has no unified treatment, clinical in accordance with the early application of different drugs, but in general to anti-inflammatory and analgesic, commonly used with non steroidal anti-inflammatory drugs, traditional anti rheumatic drugs, biological agents, these drugs have many adverse reactions, such as the digestive system, nervous system side effects, easy to cause two damage to patients. Because of the advantages of acupotomy side effect is small, curative effect is distinct, simple operation, cost than drug therapy should be low, so this study hope through the observation of acupotomy in treating ankylosing spondylitis and explore the treatment curative effect, course of treatment, treatment, and the contrast drug therapy and for the future of traditional Chinese medicine and Western medicine combined with ankylosing spondylitis pave the way for the development.MethodFrom March 2014 to December 2014,60 patients with ankylosing spondylitis were randomly divided into control group and treatment group (30 cases), treatment group:24 cases, female 6 cases, age 17 to 40 years old, average (27.274.54) years old, duration 1 years to 19 years, average (6.17+3.61) years. Control group:23 males,7 females, aged from 18 to 40 years, average (4.82+26.10) years old,6.87 years to 18 years, the average (1+4.03) years, the two groups in gender, age, course of disease and other clinical data compared, the difference was not significant (P>0.05).Treatment group and control group were given to improve the condition of essential drugs non-steroidal anti-inflammatory drugs:ibuprofen capsules for oral treatment group were obvious pain point tenderness with knife therapy, and both sides of the spine band sacroiliac joint region needle. Based on patient tolerance select 12 reaction sites, the needle to the lesion site anchored four consecutive vertebrae as the entry point, divided into two groups: the first group:the spine ligament (4), transverse ligament (8), a second group:between spinal ligament (4), facet joint (8). According to the specific circumstances of the patient,1-6 second choice of the first set of reaction points,7-12 second selection of the second set of reaction point, replace a set of six times per reaction sites, and so on. The control group injected with the following benefits etanercept compare the efficacy of the two groups after three months. Observation indicators BASFI, BASDAI, duration of morning stiffness, Schober test, chest expansion, referring to the distance, ESR and CRP, peripheral joint pain and tenderness index (NRS) and the like.RsultsThe treatment group:obvious effective rate was 53.3%, effective rate was 33.3%, no efficiency was 13.3%, the total efficiency of 86.7%; control group: the effective rate was 33.3%, effective rate was 30.0%, no efficiency was 36.7%, the total effective rate was 63.3% The results of the two groups after treatment compared with the treatment group than the control group, the difference was significant (P<0.05). Clinical comparison of the main indexes, the treatment group and the control group before treatment and after the t-test, the differences in the indicators of patients BASFI, BASDAI, time of morning stiffness, pain index (NRS), chest expansion, refers to the distance, Schober test, ESR, CRP and no significant difference (P> 0.05). After the treatment results by t-test, the treatment group and control group before and after the treatment with BASFI, BASDAI, time of morning stiffness, pain index (NRS), chest, refers to the distance, Schober test, ESR, CRP treatment before were improved obviously. The difference was significant (P< 0.05); but treatment group after treatment and the control treatment group compared to the results, the t test, the difference is significant (P< 0.05), the treatment group curative effect surpasses the control group. In the treatment group, the BASDAI activity index from the original moderate to mild pain, and the control group after treatment BASDAI activity index is still moderate pain, the treatment group after treatment, the control group was treated with normal value. After treatment, the treatment group was treated with normal value. After treatment, compared with the control group, ESR decreased to normal, while the control group was still higher than the normal value.ConclusionNeedle knife therapy in the treatment of ankylosing spondylitis patients with good curative effect, the total efficiency is better than that of the control group and in the improvement of the clinical indicators, acupuncture therapy is superior to drug therapy. Compared with drug therapy more side effects, acupotomy therapy not only adverse reaction is little, obvious curative effect, can significantly improve the patient's quality of life, and it is easily accepted by the patients, worthy of promotion. The observation time is short, although the short-term effect is good, but the long-term effect is also need to be further observed, at the same time because of the limited number of samples, hoping to expand the number of samples in the future, to provide accurate evidence for evidence-based medicine, improve the quality of life in patients with ankylosing spondylitis, improve the quality of life, play a new way of treating ankylosing spondylitis... |
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