Research On Traditional Chinese Medicine Syndrome Rules Of Chronic Primary Glomerulonephritis

Objective: This study is to research the TCM syndrome rules of primary glomerulonephritis.Through the observation of 200 cases of patients with CPGN,We expect to investigate the relationship between TCM syndrome and western medicine type of objective indicators.In order to make some contribution to the combination of TCM syndrome and modern medicine microscopic macroscopic differentiation criteria.Methods: The design of clinical trials,this experiment included 200 CPGN patients who were treated in Hubei Provincial Hospital Of Traditional Chinese Medical from 2013.5 to 2015.7.According to the data analysis,We find the relationship between syndrome type distribution and many affecting factors.Result:1.Among 200 cases of CPGN patients,present with spleen and kidney Qi deficiency is most common(87 cases accounted for 43.5%);and Excess heat in the most common,(77 cases accounted for 38.5%).This deficiency can be arbitrary and standard empirical phase and folder,where more heat and spleen and kidney Qi Yin deficiency and sandwiched,lung and kidney qi deficiency and dampness more sandwiched,more bleeding and Yin Deficiency sandwiched;empirical standard of between each other and folders can be to heat,blood stasis,dampness-based mutual folder.2.On the CKD staging,this deficiency and the standard empirical distributions were different.In the distribution of this deficiency,CKD1 appears more common in patients with spleen and kidney Qi,CKD2 patients with spleen and kidney Qi and spleen deficiency more common,CKD3 of patients with liver and kidney Qi and more common,CKD4 patients with liver and kidney Qi common.On the distribution of standard empirical,CKD1 period in order to heat and moisture more common,CKD2 more common in hot and humid period,CKD3 period bleeding more common in hot and humid,CKD4 period to dampness and blood stasis common.3.On the Western pathological type,no difference in the distribution of this deficiency,there are marked differences in the empirical.On the distribution of standard empirical,MCD in all wet card,MsPGN to the main heat syndrome,FSGS mainly to heat and blood stasis,MN in humid,wet muddy and bleeding are more wet card minimum.4.Among 200 cases of CPGN patients,on the common symptoms of each frequency appears top ten were fatigue,weak waist,red yellow urine,sticky mouth pain,edema,minimalist looking,frequent nocturia,oropharyngeal drying,irritability,dizziness,ringing in the ears,mainly mild to moderate degree to severe rare.5.On the age and sex distribution,sex distribution,gender and type of TCM was no significant correlation between age and TCM syndrome correlated.This deficiency,the highest average age group Qi,spleen and kidney and liver and kidney group Secondly,spleen and kidney Qi group,the average age of the lowest.Positive mark,the highest average age group,blood stasis,dampness group Secondly,moisture mean age minimum.6.Syndrome Type and hemoglobin,uric acid,24-hour urine protein excretion was correlated with urinary occult blood qualitative no correlation.(1)Qi Yin deficiency group hemoglobin levels lower than non-group,dampness group hemoglobin levels lower than non-dampness group;(2)Spleen deficiency group serum uric acid levels than non spleen deficiency group,group Qi Yin deficiency serum uric acid levels than non-group,heat group serum uric acid levels than non-heat set,wet muddy The serum uric acid levels than non-dampness group;(3)On the distribution of urinary protein level,this deficiency with the standard empirical distribution were different,24-hour urinary protein were less than 1g for Group A,between 1g~3.5g person for the group B,which is greater than 3.5g for C group.In the distribution of this deficiency,group A of spleen and kidney Qi is the most common,in Group B with spleen and kidney Qi and Yin Deficiency is more common,in group C to Qi and Yin Deficiency is most common.On the empirical distribution label,group A with hot and humid blood is most common,group B with damp-heat syndromethe occurs most,group C the damp-heat syndrome is most common,followed by wet card;(4)The different levels of occult blood in urine qualitative has no obvious regularity with TCM Syndromes.Conclusion:1.Chronic primary glomerulonephritis syndromes main deficiency in the present,in which the spleen and kidney Qi is the most common type of witness,Qi and Yin deficiency disease more common in middle and late.Positive mark to heat the main,throughout the course of the disease,suggesting that the cause of heat is the key cause kidney damage,damp places late in the disease,blood stasis,dampness each node based.2.CKD stage,age,and the disease of syndromes have some relevance,pathological type and distribution of TCM labeled Positive correlation between clinical indicators commonly used to detect hemoglobin content,blood uric acid level and the level of quantitative proteinuria and TCM distribution correlation,can provide a basis for TCM syndrome type.3.Gender has no correlation with the TCM Syndrome,Pathological type has no correlation with the TCM Syndrome,the different levels of occult blood in urine and qualitative level with the TCM Syndromes has no correlation.