Clinical Analysis Of The Curative Effect Of Noninvasive Assisted Ventilation For Little Infants With Severe Pneumonia

Objective : Through comparing regular treatment with Continuous Positive Airway Pressure(CPAP)in terms of oxygen partial pressure(PaO2),breathing,heart rate,pulmonary rale,hospital discharge,this thesis investigates the significant role of CPAP in curing little infants with severe pneumonia.Methods :In the thesis,69 little infants hospitalized from November,2014 to February,2015 were divided at random into two groups---the control group with 35 ones and the experimental group with 34 ones.Both groups received comprehensive therapy which included using anti-infectious ceftazidime,strengthening management of respiratory tract with budesonide as well as hydrochloride bromine ammonia pump suction and protecting the organ functions of the heart,the liver and the kidney etc.Apart from comprehensive therapy,the control group was given oxygen through nasal catheter or facemasks while the experimental group was given non-invasive assisted ventilation.Meanwhile,oxygen partial pressure,breathing,heart rate,dyspnea,pulmonary rale and chest radiographs were observed.Statistically,both groups showed no great difference in gender,age and severity of illness.During the treatment,five little infants,one in the experimental group and four in the control group,were given tracheal intubation and respirators due to intensified dyspnea.Besides,two little infants were transferred to superior hospitals and another two little infants,one in each group,stopped receiving treatment for economic conditions.As a result,there are 30 little infants left in each group who were analyzed in the thesis.The software SPSS 16.0 was employed for the statistical analysis and the result showed normal distribution.Mean plus or minus standard deviation is adopted to denote quantitative data.The statistical method is to examine the two samples by means of t method.In case of variance of data,nonparametric analysis was adopted.P<0.01,Analysis revealed that the difference was of statistical significance.Results:1 The recovery time of oxygen partial pressure in the experimental group was 5.80 plus or minus 2.09 hours,less than 11.73 plus or minus 3.51 hours in the control group,P<0.01,the difference was of statistical significance.2 The recovery time of heart rate in the experimental group was 3.03 plus or minus 1.06 days,less than 4.73 plus or minus 1.14 days in the control group,P <0.01,the difference was of statistical significance.3 The recovery time of respiration in the experimental group was 4.50 plus or minus 0.93 days,less than 5.87 plus or minus 0.86 days in the control group,P<0.01,the difference was of statistical significance.4 The relief time of dyspnea in the experimental group was 4.03 plus or minus 0.92 days,less than 5.67 plus or minus 0.88 days in the control group,P <0.01,the difference was of statistical significance.5 The time required for lung rale to disappear was 7.13 plus or minus 1.16 days in the experimental group,less than 9.00 plus or minus 1,43 days in the control group,P<0.01,the difference was of statistical significance.6 The time of chest radiograph recovery was 11.4 plus or minus 1.65 days in the experimental group,was 11.7 plus or minus 1.73 days in the control group,P?0.05,the difference was no statistical significance.7 The time of discharge time was 11.67 plus or minus 1.66 days in the experimental group,was 12.37 plus or minus 1.73 days in the control group,P?0.05,the difference was no statistical significance.Conclusion:The CPAP treatment worked well in that it could reduce the recovery time of oxygen partial pressure,breathing and heart rate,accelerate the relief of dyspnea and reduce the use of tracheal intubation.Nevertheless,it failed to improve the conditions shown in chest radiographs,nor shorten the patients' stay in hospitals.