Analysis Of Clinical Features Of Patients With Anterior Circulation Infarction With Calcification Of Intracranial Segment Of Internal Carotid Artery

Objective:To investigate the clinical characteristics of intracranial segment of internal carotid artery calcification in patients with anterior circulation infarction,clear effects of intracranial vascular calcification of anterior cerebral circulation infarction patients,in order to control the risk factors,to assist in the diagnosis and treatment,reduce disability rate,improve prognosisMethods: Using retrospective study method,collecting June 2013 November2015 Dalian Medical University Second Affiliated Hospital Department of Neurology of 141 cases of cerebral circulation infarction patients.Collect and collate the relevant clinical information,including gender,age,history of hypertension,history of diabetes,high cholesterol disease history,smoking status,admission when the National Institutes of Health Stroke Scale(National Institutes of Health Stroke Scale(NIHSS)score,the discharge NIHSS score and admission NIHSS score difference,discharge modified Rankin scale(modified Rankin Scale(MRS)score.According to the in multislice spiral CT(computed tomography)with and without vascular calcification,divided into existence of calcification of the intracranial portion of the internal carotid artery in anterior circulation infarction group and no intracranial segment of internal carotid artery calcification anterior circulation infarction group(group of calcified and non calcified group.In multi-slice spiral CT of the pituitaryfossa level.The maximum diameter of the measurement in patients with calcified,with maximum diameter of 1mm limits,maximum diameter of less than 1mm of calcification group division for mild calcification group,than 1mm of the calcification group for patients with severe calcification group.Using statistical methods baseline data of different groups,toast(trial of org10172 in acute stroke etiology typing,NIHSS scores on admission,discharge NIHSS score and admission NIHSS score difference and mRS score of comprehensive analysis.Results:1?In the study,141 patients with anterior circulation infarction were collected,36 were in the calcified group and 105 in the non calcified group.compared between the calcified group and the non calcified group in terms of gender,age,history of hypertension,history of diabetes,high cholesterol disease history,smoking status,admission when the National Institutes of Health Stroke Scale(National Institutes of Health Stroke Scale(NIHSS)score.There were significant differences between the two groups in the aspects of hypertension,diabetes,and high cholesterol levels of two yuan Logistic regression analysis,there was statistical significance,P value of each group <0.05.2?18 patients(52.3%)calcification group in large artery atherosclerosis type(Large-artery atherosclerosis in LAA),small artery occlusion(Large-artery atherosclerosis SAA)in 12 cases(38.9%),6 cases(16.7%)of other types;non calcification group of large artery atherosclerosis in 57 cases(54.2%),small artery occlusion type 23 cases(21.9%),other types of 25 cases(23.8%).The difference was not statistically significant between the two group3?Discharge NIHSS score and admission NIHSS score difference between the two groups(P value <0.05)were analyzed in the patients with calcification group and non calcified group.Of two groups at discharge mRS scores analysis,calcification group in patients with good prognosis accounted for 38.9%,61.1% in patients with poor prognosis;non group in good prognosis patients accounted for 80.0%,poor prognosis patients accounted for 20.0%.Two groups of mRS score(P < 0.05).4?Admission NIHSS scores were compared between the mild calcification group and the moderate and severe calcification group,the mild calcification groupwas(3.90 + 2.02)score,the moderate and severe calcification group was(7.44 +4.52)score,the difference between the two groups(P<0.05).In the etiology of TOAST,mild calcification group and moderate to severe group composition of different,mild calcification group LAA accounted for 30%,the moderate and severe calcification group LAA about 75%,there is statistical significance(P<0.05).5 ? Discharge NIHSS score and admission NIHSS score difference value,the mean value of in patients with mild calcification was(1.000± 1.076),the mean value of the moderate and severe calcification group was(2.313 + 0.6021);the two groups were statistically significant(P = 0.0173).Of two groups at discharge mRS scores analysis,mild calcification group in good prognosis 60.0% and the poor prognosis and 40.0%;the moderate and severe calcification group showed good prognosis accounted for 12.5% and the poor prognosis is accounted for 87.5%,between the two groups have statistical significance.Conclusions:1?High blood pressure,high cholesterol,and diabetes are risk factors for carotid artery calcification in the anterior circulation.2?Compared with no calcification in patients with intracranial segment of internal carotid artery calcification in patients with anterior circulation infarction.Most patients with neurologic impairment was not significantly improved or aggravate the situation and defect of nerve function after stroke recovery is poor.3?In the intracranial segment of the internal carotid artery calcification degree is more serious,the more severe neurological deficits,the discharge time of the nerve function defect is more serious,the recovery of neurological function after stroke is poor,the prognosis is poor.