Stenotrophomonas Maltophilia Infections: An Analysis Of Clinical Characteristic And Risk Factors And The Prognosis

Objective:To investigate the clinical characteristic, risk factors, the prognosis and antibiotic resistance of Stenotrophomonas maltophilia (SMA) infections to provide evidence for rational antimicrobial therapy and prevention of S. maltophilia infections.Methods:A retrospective analysis was carried out on 129 S. maltophilia infections inpatients from November 2013 to April 2014, from the first hospital affiliated to Zhejiang University School of Medicine.Results:The average age of 129 S. maltophilia infections cases was (65.1± 17.0) years.100 out of 129 patients were lower respiratory tract infection, the remains were non-respiratory tract infection. Primary pulmonary disease ratio, length of ICU stay, tracheotomy ratio, usage ratio of broad-spectrum antibiotics, age of onset were higher in patients with lower respiratory tract infection. However, among non-respiratory tract infection patients usage ratio of immunosuppressive agents, surgical operation and catheterization aseptic chamber proportion were higher. The mortality of patients treated with susceptible antibiotics after infection were lower than that without effective therapy.Conclusion:The risk factors of the patients with lower respiratory tract infection wereprimary pulmonary diseases, check in ICU, tracheotomy, usage of antibiotics, and morbidity age, The risk factors of the patients with non-respiratory tract S. maltophilia infection were surgical operation, catheterization inside aseptic chamber, and intake of immunosuppressive agents. The use of susceptible antibiotics therapy can effectively reduce the mortality of the patients with S. maltophilia infection.