Ketosis is a nutritional deficiency diseases of high-yield dairy cows during postpartum,which can seriously affect the health of dairy cows and economic benefits of cattle farms and restrict the development of dairy industry.Due to the serious harms of ketosis,the prevention of ketosis of dairy cows is very important.The aim of this study is to research postpartum health additives.In this study,postpartum health additives were analyzed by comparing the differences of blood biochemical indexes,ketosis morbidity,elimination rate,reproductive performance and lactation performance between the experimental group and the control group,to evaluate the effect of postpartum health care additives on the prevention of ketosis.At the same time,a significant effect and high ratio of postpartum care additives found by comparing three groups of postpartum care additives,which can provide a suitable additive for postpartum care scale pasture and a theoretical basis and the specific implementation plan for the cows’ perinatal care.Twenty-five healthy dairy cows including 15 cows on experimental group(A,B,C),5 cows on commoditized control group(D)and 5 cows on control group,were selected from a large scale dairy farm,which parities range from 2 to 4,body score range from 3 to 3.5.The postpartum cows of group A were orally administered the calcium citrate mixture,the group B were orally administered propylene glycol mixture,the group C were fed solid particles of propylene glycol mixture,the group D were orally administered commercial health care additives and the control group were orally administered same warm water compared with other group.The blood samples were collected from each cow on-7 d and-1 d during prenatal,0 d(parturition)and 1 d 3 d,5 d,7 d,10 d,13 d,17 d and 21 d during postpartum,respectively.Then serum were collected by centrifugation.Detected BHBA,NEFA,GLU,AST,Ca and so on contents in serum.Recorded indexes of milk performance and reproductive performance of dairy cows in this parity and computed the incidence of ketosis and elimination rate in this study.The results showed that the BHBA content in group A was significantly lower than that in the control group on day 10 postpartum(P < 0.05).The BHBA content in group B was significantly lower than that in the control group on day 7 and 13 postpartum(P < 0.05).The BHBA content in group C was very significantly lower than that in the control group on day 7 postpartum(P < 0.01)and significantly lower than that in the control group on day 17 postpartum(P < 0.05).And the BHBA content in group D was significantly lower than that in the control group on day 5,7,10 and 17 postpartum(P < 0.05).There was no significant difference in BHBA content between the three experimental groups on day 21 postpartum(P > 0.05).The concentration of BHBA in group A and group B was slightly higher than that in group D,and the concentration of BHBA in group C was close to that in group D.The NEFA content in group A was very significantly lower than that in the control group on day 10 postpartum(P < 0.01).The NEFA content in group B was significantly lower than that in the control group on day 10 and 17 postpartum(P < 0.05).The NEFA content in group C was significantly lower than that in the control group on day 10 and 17 postpartum(P < 0.05).The NEFA content in group D was very significantly lower than that in the control group on day 10 and 21 postpartum(P < 0.01)and significantly lower than that in the control group on day 17 postpartum(P < 0.01).The level of GLU in group A and D were significantly higher than that in the control group on day 3and 5 postpartum(P < 0.05)and very significantly higher than that in the control group on day 7 postpartum(P < 0.01).The level of GLU in group B were significantly higher than that in the control group on day 3,5 and 7 postpartum(P < 0.05).The level of GLU in group C were very significantly higher than that in the control group on day 3and 5 postpartum(P < 0.01)and significantly lower than that in the control group on day 7 and 10 postpartum(P < 0.05).On day 21 postpartum,no significant difference was found in group A and C compared with group D(P > 0.05),and the Ca content in group C was slightly higher than that in group D.The Ca content in group B was significantly lower than that in group D on day 1 and 3 postpartum(P < 0.05).The Ca content in group B was slightly higher than that in the control group,and no significant difference between the two groups(P > 0.05).In conclusion,the mortality,milk performance and economic benefits of group C were better than of group A,B and D.The dairy cows with health care during postpartum were better than the control group on biochemical indexes,ketosis rate,lactation performance and reproductive performance.Among the three health care additives,the propylene glycol mixture have the most significant effect on the prevention of ketosis,which have the greatest effect on the production performance and can obtain excellent economic benefits.In addition,it is convenient for feeding and feed additives.So it is suitable for clinical application and can be used as a postpartum health care additive. |