| The safety of animal derived food is a central point of the world and an important public health problem.Antibiotic residue in animal derived food and antibiotic resistant bacteria are threatens to our human beings.It is an effective way to reduce or replace the use of antibiotic in animal husbandry.This study investigate the effects of bile salt hydrolase inhibitor on broiler and layers and the possibility of application in poultry production.The results we obtained would provide scientific and theoretic basis for reducing antibiotic use and ensuring food safety.Experiment 1:Effects of emulsifier and BSHI on broiler performance and blood parameters..Emusifier and BSHI were added to basal feed in the amount of 400 g/T.A total of 234 Broilers were randomly divided into 3 groups,each group with 13 replicates,and 6 chickens per replicate Different diets were fed:(1)blank group:basal diet;(2)emulsifier group:basal diet + 400g/T emulsifier;(3)BSHI group:basal diet + 400g/T BSHI;The results showed that the effects of BSHI and emulsifier on feed conversion and average daily weight gain were not significant(P>0.05),but BSHI could increase feed conversion,while emulsifier decrease.The effect of emulsifier and BSHI on blood parameters of broiler was also not significant(P?0.05),Experiment2:Comparing the effects of BSHI on the performance of broiler fed diets at different energy levels.A total of 312 chickens were randomly divided into 3 groups,each group with 13 replicates,and 6 broilers per replicate.,Different diets were fed:(1)BSHI1 group:basal diet + 400g/t BSHI(2)BSHI2 group:basal diet basis-50kCal energy/T +400g/T BSHI;(3)BSHI3 group:basis diets-100kCal energy/T + 400g/T BSHI;(4)control group:Basal diet 100kCal/T energy;The results showed that there was no significant difference between these treatments,in terms of feed conversion rate and average daily weight gain(P?0.05),but feed conversion rate decreased with the decrease of energy in diets.Blood parameters also showed no significant difference between the treatments(P?0.05).It was no significant interaction between the energy level of broiler diets and the addition of BSHI in terms of production performance and blood parameters.Addition of BSHI in the diet had no effect when energy was low.Experiments:The effects of BSHI on production performance and blood index in later laying hens.Layers were divided into two groups,with 5 replicates each group and 48 layers each replicateDiets:(1)blank group:basal diet;(2)chromium yeast group:basal diet + 300 g/T chromium yeast;(3)yeast hydrolysate group:basal diet + 300 kg/T yeast hydrolysate;(4)BSHI group:basal diet + 300 g/T BSHI;The results showed that there was no significant difference between the two groups in the total egg weight,egg production rate,egg mass,and average egg weight(P?0.05).However,BSHI could increase the body weight of laying hens.Compared to blank group,the body weight of the BSHI group increased by 0.05 kg,which was 350.0%higher than that of the blank group.The effect of BSHI on the blood index of laying hens was not significantly different(P?0.05),but the content of IgG in BSHI group was 66.5%higher than that in blank group.Addition of BSHI to broiler diets can improve the performance of broilers and blood parameters,and the supplement of BSHI to high fat diets is more meaningful for improving production performance.The addition of BSHI to the laying hens diet had no significant effect on the laying performance,but it could improve the immunity and weight of the laying hens.The results indicated that BSHI can replace the use of antibiotic growth promoters in broiler production,increase the absorption and utilization of energy raw materials,and increase the self-immunity of laying hens... |
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