The Development Of Traditional Chinese Herbology Injection In Dairy Cow Mastitis

Cow mastitis is a complex problem that seriously affecting the benefits of dairy farms. Generally,effective treatment of cow mastitis is western medicine(antibiotic) therapy in recent years, despite it's effect is good, drawback has emerged, for example antibiotic residues and drug resistance. How to At this stage Looking for a Safe and effective treatment is important at the condition that food safety problem has became increasingly serious. Chinese herbal medicine treatment received more attention because of it's safety, no drug residues and low cost.Traditional dairy cow mastitis preparations are generally powder?mastic?water decoction. Due to the weakness that large volume,difficult to store and transport,not easy to operation in old preparations,the need of new preparation that convenient,easy to carry and operation is urgent.Traditional Chinese medicine injection solved this problem because of it's small volume,easy to storage, convenient to use and rapid effect.The determine of prescription is depend on Chinese medicine theory,data collection and preliminary test.This experiment select boiling method to extract active ingredient,purification extraction after incrassation.We obtain a result that modified gelatin precipitation method has a very good effect on extraction purification by comparison precipitation capacity?clarity antimicrobial effect?tannin and protein examination.Quality inspection and security check of the injection are qualified according to Chinese pharmacopoeia.Experimental study on pharmacodynamics of injection show that the MIC/MBC result of Staphylococcus aureus, Escherichia coli, streptococcus is 0.0625/0.1250(g/mL),0.0625/0.1250(g/mL), 0.1750/0.2500(g/mL),the diameter of inhibition zone result is 12.7±0.17mm?12.3±0.17mm? 10.7±0.33mm.Vascular permeability and spleen weight increasing experiment show that spleen index can significant increase and vascular permeability significant decrease after inject this injection.Indicate the injection has some effect on immunologic enhancement and anti-inflammatory action.