Antibacterial Effect Of Enramycin And Its Applicati On In Animals Production

Enramycin has a great ability to promote growth performance and improve feed conversion because of its special function of anti-bacteria, which is applied for feed as a kind of new additive. However, a large number of Enramycin products rush into the market, causing products chaos in market, as a result Enramycin products needing to optimize formula. The present test one was carried out to compare the Minimal Inhibitory Concentration(MIC) of three kinds of Enramycin coming from different companies(I,?,?) to A- type Clostridium perfringens, C-type Clostridium perfringens, Bacillus subtilis MIC, in order to determine the optimum ratio of effective component of Enramycin.Results showed that when the best ratio of effective components A/B of Enramycin I was 4.0, the MIC to Clostridium perfringens type A was 0.0800?g/mL. When the ratio of A/B was 4.5, the MIC to Clostridium perfringens type C was 0.1280?g/mL. When the the ratio of A/B was 3.5, the MIC to Bacillus subtilis was 0.1075?g/mL.The test two was carried out to compare the using effect of Enramycin with other four kinds of marketable antibiotics on piglets and AA broiler, in order to get the optimal proportion of Enramycin in actual application.Results showed that when the dosage of Enramycin premixes in piglet diets in treatment group was 12mg/kg, their daily gain, feed intake, feed conversion rate and rate of diarrhea were better than avila azithromycin group, virginia toxin, bacitracin zinc group, and west peptide group.When the dosage of Enramycin premixes in 1~21 day-old broiler diets was 8mg/kg, broilers' daily gain and feed conversion ratio were better than avila toxin and virginian drug group.When the dosage of Enramycin premixes in 22~42 day-old broilers diets was 6mg/kg, piglet's daily gain, feed intake, feed conversion rate and rate of diarrhea were better than Enramycin ? group and ? group.