Azidation Of Olefins Under Visible Light Photoredox Catalysis

Organic azides are synthetically very useful as the precursors of nitrogen-containing organic molecules.This thesis mainly deals with free radical methods for the preparation of organic azides via azidation/difunctionalization of olefins.It consists of the following two chapters:The first chapter gives a brief review of the free radical methods developed in recent years for the preparation of organic azide compounds,which is introduced from the following three aspects:（1）preparation of organic azides by addition of the azidyl radical to the carbon-carbon double bonds;（2）preparation of organic azides by the azide transfer reactions;（3）preparation of aryl azides.The second chapter describes my research work on the Zhdankin’s reagent-mediated azidation of olefins under the conditions of photoredox catalysis.We found that by the catalysis of Ru（bpy）₃Cl₂,N-vinylbenzene sulfonamides can react with Zhdankin reagent under visible light irradiation to afford the azidation/acyloxylation products in acetonitrile.The reaction has the merits of high regioselectivity,mild conditions and atomic economy.This method provides a new way for building azidyl and oxy-difunctionalized compounds from olefins.