Palladium(Ⅱ) Catalyzed Nucleophilic Addition

The thesis is focused on the palladium（II）-catalyzed nucleophilic addition of arylboronic acids toα,β-unsaturated compounds.1.In-Situ Generated Cationic Pd（II）Catalyzed Nucleophilic Addition of Arylboronic Acids to N-Sulfonyl-Arylaldimines.In-Situ generated cationic palladium（Ⅱ）-catalyzed addition of arylboronic acids to N-Sulfonyl-Arylaldimines has been developed in an efficient and convenient way.It can avoid complicated experimental procedures and the low yield of synthesis the cationic Pd（II）.Meanwhile,a high yield achieved when we use low coordination ability solvent CH₃NO₂ as solvent.2.Pd（II）/Bipyridine-Catalyzed Conjugate Addition of Arylboronic Acids toα,β-Unsaturated Carboxylic Acids.Pd（II）/Bipyridine-Catalyzed conjugate addition of arylboronic acids toα,β-unsaturated carboxylic acids was developed and optimized with Pd（OAc）₂/bpy as catalytic system and THF/HOAc/H₂O as solvent.It is a convenient and efficient way to synthesizeβ,β-disubstituted carboxylic acids but is little investigated.