Nickel-Catalyzed Activation And Transformation Of C-N And C-S Bonds

This paper describes the reaction of transition metal nickel compounds to catalyze the fragmentation of aromatic inert carbon heteroatom bonds to synthesize new compounds containing carbon-carbon bonds.Chapter one introduces the coupling process of aryltrimethyltrifluorome-thanesulfonate ammonium salt and organoaluminum reactants to promote the activation of aryl C-N bonds and the formation of new carbon-carbon bonds.The method has a large reactant type,including various types of aryl trimethyl trifluoromethanesulfonic acid ammonium salts,which are well involved in the coupling reaction;alkylaluminums containing both β-H-containing alkylaluminums can be used as nucleophiles.At the same time,the catalytic system can also be used for the partial coupling of partially aromatic aluminum reagents and aryl trimethyl trifluoromethanesulfonates to obtain the corresponding coupling products.Chapter two describes the coupling reaction of nickel catalyzed methyl sulfide compounds with organic lithium reagents.Various substituted arylmethyl sulfide compounds can be used as electrophilic reagents,can react and get the corresponding product.A variety of organo-lithium reagents have a certain degree of nucleophilicity,and can successfully participate in the reaction to get a good yield of the corresponding product.This work also found that zero-valent nickel could also effectively catalyze the coupling of lithium reagents with aromatic thioether compounds by the addition of additional antimicrobial reagents in the absence of additional ligands to obtain a better yield of silane compounds.