Preparation And Property Of Hydroxyapatite And α-Hydrogen Zirconium Phosphate Nanocomposite Hydrogels

Nanocomposite hydrogel (NC) has high mechanical strength, high water absorption, water retention, medicine-controllable release with unique three-dimensional network. The rodlike and needlelike hydroxyapatitile (HA) has been prepared by hydrothermal and template method respectively. The HA prepared by the template has higher crystallinity, purity, thermal stability, dispersion in water by the test of dispersion, XRD and SEM. The nanocompostie hydrogel of PAM-HA has been prepared by in-situ polymerization of acrylamide (AM) with dispersed HA in water using composite initiator of potassium persulfate (KPS) and sodium bisulfite (SBS). The PAM-HA nanocomposite hydrogel has excellent anti-fatigue, mechanical properties with the elongation at break of 1570.76%%, tensile modulus of 61.41 KPa, maxium tensile strength of 957.86 kPa by the test of universal tensile, tensile test with nod, load tensile, compression and recycle tensile test. The prepared hydrogel has three dimensional network verified by SEM of the dry-freeze samples. The a-ZrP has been prepared by the hydrothermal method by the ZrOCl2·8H2O and phosphate. The yields of the a-ZrP-3M and a-ZrP-6M prepared by 3M and 6M phosphate were 88.1% and 95.8% respectively. The a-ZrP-3M and α-ZrP-6M are hexagonal structure with the size of 100-500 nm and 500 nm. The nanocomposite hydrogels of PAM-ZrP(3M)-10、PAM-ZrP(3M)-20、PAM-ZrP(6M)-10 and PAM-ZrP(6M)-20 were prepared using monomer AM, allylaime exfoliated a-ZrP-3M or a-ZrP-6M by in-situ polymerization. The PAM-ZrP(3M)-20 has the best mechanical properties with breaking elongation of 1990.76%, tensile strength of 2766.34 kPa, tensile modulus of 147.68 kPa.