Firing Pattern And Synchronization Kinematic In Olfactory Bulb Neural System

The olfactory system is a very important part of biological sensory nerve system.It can help us distinguish different odors.We call it the sense of smell.Odor molecules go into the nasal cavity with airflow,and then contact with the olfactory receptor.Olfactory receptor will change the chemical signals into electrical signals,and then pass it to the olfactory bulb.All kinds of neurons in the olfactory bulb interact with each other to form the corresponding space-time coding.The information processed will be passed to the olfactory cortex and then form the sense of smell.And as the first processing structure,the olfactory bulb plays a very important role.During the process of signal transduction in olfactory nerve system,the change of synchronous oscillatory kinematic pattern of mitral cells is very important for coding and decoding in the olfactory bulb.At the same time,synchronous oscillatory kinematic pattern of mitral cells is closely related to granule cell and periglomerular cell.So,it is very important to analyze the interaction between mitral cells,granule cell and periglomerular cell.We set up a network model of olfactory bulb including the three kinds of cells for further discussion,too.This article firstly tells the story of physiological anatomy structure of olfactory system and mechanism of smell formation,and then introduces the development and research status of the model of the sense of smell.Secondly,this article introduces the research status and the main research methods of neural coding.Thirdly,we introduce the olfactory system dynamic model and analyze the the dynamic model of mitral cell,granular cell and periglomerular cell in detail.Through the numerical simulation,we get the firing pattern of mitral cell,granular cell and periglomerular cell.Finally,we set up the electrophysiological model of olfactory bulb to comparing the difference between the firing patterns of different cells and the difference under the condition of network or not.In addition,we analyze the synchronization kinematic of MCs,finding that the inhibitory effect of GC and PGC contributes to the synchronization kinematic of MCs.These findings can help us understand the working mechanism of smell better.The research of this topic can help us.to have a better understand about mitral cell,granular cell and periglomerular cell.And we learn that there is interaction between these three cells.All of these can help us to know more about encoding process of olfactory information,and lay a solid foundation for further study.In the following work,we will set up a more complete model of the sense of smell.This model will include three part respectively are osmoceptors,olfactory bulb and olfactory cortex.Osmoceptors will transform scent signals to electrical signal.The olfactory bulb will process smell information further.The olfactory cortex will process the olfactory information further and form the sense of smell finally.Thus we can make an overall research on the formation mechanism and encoding process of the sense of smell.