The Design Of Sweep Source Optical Coherence Tomography And 3-D Reconstruction

Optical coherence tomography(OCT) is a non-contact, non-invasive imaging modality with the micrometer resolution, which can be used to obtain the internal structure and function images of the biological tissues. Swept source OCT is ont of the Fourier domain OCT. Compared with Time domain OCT, it has the advantages of higher imaging rate and sensitivity compared with Time domain OCT and play an important role in the field of ophthalmology and Cardiovascular. It uses the two-dimensional tomography images to obtain disease information. 3D reconstruction of two-dimensional tomography OCT images has important applications in biomedical engineering. It is widely used in diagnosing, surgery planning, simulating and teaching etc. This paper focuses on the design of SS-OCT system, the 3D reconstruction and interaction of two-dimensional images. The main work and achievement are summarized as following:1. The SS-OCT system at 1000 nm wavelength is developed, which consists of a fiber interferometer and a swept source. This paper described the overall design of the SS-OCT system, focused on describing the development of the system, and obtain the images of the mirror and cover glass. The A-scan rate of the system is 100 k Hz, the axial and lateral resolution are 5 mm and 23.9 mm, and the axial imaging range is 11 mm.2. The 3D reconstruction with two-dimensional artery images has been finished. The realization mechanism of visualization tool package based on VTK is analyzed, and the principle of volume rendering and ray casting are discussed. In the paper, under the VC++6.0 and the visual package VTK platform ray casting algorithm is adopted to reconstruct the 3D image for artery image sequence with the bmp format. The key algorithms and 3D visualization results are given. The simple interactive operations, such as rotation are realized.3. It has formed the plane excision of the 3D reconstruction target and realized the excision extraction of 3D image. The vector and inner points are used to form the visual excision plane and obtain the information of cross-section image. The ring around artery 3D reconstruction is removed by setting multiple excision plane. The 3D cross-section images is obtained. At the same time the correspondent images aredisplay in the screen. Therefore, the cross-section extraction of 3D images on 3D OCT artery reconstruction has been realized.