Effects Of 24-week Nordic Walking Exercise On Body Composition And Liver Fat Content Of Middle-aged Women With Pre-diabetes And Non-alcoholic Fatty Liver Disease

ObjectiveThe study evaluated body composition and liver fat content of middle-aged women with pre-diabetes and non-alcoholic fatty liver disease by Dual-energy X-ray Absorptiometry and 1H Magnetic Resonance Spectroscopy. In order to evaluate how 24-week Nordic walking can improve pre-diabetes and non-alcoholic fatty liver disease.Methods1. Subjects: 40 middle-aged women with pre-diabetes and non-alcoholic fatty liver disease from Yangpu District were included as subjects and randomly dicided into exercise group(E group) and control group(C group) of 20 women. During the intervention experiment, 7 women quit because disease and things. Totally 17 exercise group women(aged 60.0±3.7 years) and 16 control group women(aged 58.8±4.2 years) completed the intervention. All the subjects were voluntary and signed the information consents.2. Intervention: Nordic Walking as the main mode of aerobic exercise with stretching exercises Tai Chi exercise as preparation and finishing activities. All the subjects took exercise in the sports venues together. The intensity of the exercise increased from 60% VO2 max to 75% VO2 max, the time of the exercise increased from 45 minutes to 60 minutes, the frequency of the exercise added from 3 times a week to 5 times a week for 24 weeks.3. Publicity education: The control group received a publicity education including chronic disease prevention, health education of diet and exercise guidance. Control group were told to maintain the original level of physical activity, diet pattern and life style unchanged.4. The test measures: Dual-energy X-ray Absorptiometry was used to check the body fat ratio; fat mass and lean mass of upper limbs, lower limbs, trunk, android, gynoid, and body before and after the intervention. 1H Magnetic Resonance Spectroscopy was used to detected liver fat content non-invasively.Results1. After 24-week Nordic walking intervention, the body fat ratio and the weight of E group decreased significantly than before(p<0.05). The weight of C group increased but not significant(p>0.05). Comparison between groups, the weight of E groupdecreased than the C group, but not significant(p>0.05).2. After 24-week Nordic walking intervention, the fat mass of every one part of E group decreased significantly than before(p<0.05). The fat mass of upper and lower limbs, trunk, gynoid of C group increased significantly than before(p<0.05); the fat mass of android increased but not significant(p>0.05). Comparison between groups, the fat mass of E group decreased than the C group, but not significant(p>0.05).3. After 24-week Nordic walking intervention, the lean mass of upper and lower limbs of E group increased significantly than before(p<0.05); the lean mass of trunk, android and gynoid decreased but not significant(p>0.05). The lean mass of lower limbs and trunk of C group decreased significantly than before(p<0.05); the lean mass of uppe limbs, android and gynoid decreased but not significant(p>0.05). Comparison between groups, the lean mass of E group decreased than the C group, but not significan(p>0.05).4. After 24-week Nordic walking intervention, the liver fat content of E group decreased significantly than before(p<0.05). The liver fat content of C group increased significantly than before(p<0.05). Comparison between groups, the liver fat content of E group decreased significantly than the C group(p<0.05).5. Android fat content has highly correlation with liver fat content(R>0.7, p<0.05). Gynoid fat content has low correlation with liver fat content(R<0.4, p<0.05).Conclusion1. 24 weeks Nordic walking can significantly significantly reduced body fat ratio and body weight, body fat accumulation and visceral fat accumulation of central obesity.2. 24 weeks nordic walking can effectively increase the lean body mass of the upper and lower limbs, improve the energy metabolism of the body movement.3. 24 weeks Nordic walking can effectively improve the liver fat content of nonalcoholic fatty liver disease.4. As android fat content has highly correlation with liver fat content, it can be an auxiliary judgment for non-alcoholic fatty liver disease.