The Relationships Among Resilience, Health-promoting Behaviors And Quality Of Life In Rectal Cancer Patients Receiving Neoadjuvant Therapy

ObjectiveTo investigate the status of resilience, health-promoting behaviors and quality of life in rectal cancer patients receiving neoadjuvant therapy. Further, to explore the relationship between resilience and health-promoting behaviors, also the relationship between resilience and quality of life. Finally, to analyze the modifying variables of health-promoting behaviors and quality of life.Methods112 newly diagnosed rectal cancer patients receiving neoadjuvant therapy were included with convenient sampling during November 2013 to September 2015. All participants were tested with subjects’ demographic characteristics, the Chinese version of Connor-Davidson Resilience Scale(CD-RISC), Health-Promoting Lifestyle ProfileⅡ(HPLPⅡ) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30(EORTC QLQ-C30) to explore the relationships among resilience, health-promoting behaviors and quality of life. All data were analyzed by SPSS version 17.0. The main methods included: t test, one-way analyses of variance(ANOVA), product-moment correlation coefficient and multivariate linear regression. The level of the test was 0.05.Results1. For these patients, the total score of resilience was lower than norms in China(58.14±10.66 vs 65.4±13.9, P<0.001).2. The total score of health-promoted behaviors was(115.99±15.79). Among the six factors, the score of interpersonal support(21.69±3.60) was the highest, however, the score of health responsibility(19.17±3.56) and physical activity(14.87±3.81) were lower than the others.3. The score of general quality of life was lower than norms in China(55.51±12.59 vs60.7±23.4, P<0.05). Besides, the score of functioning dimension was lower. In terms of symptom dimension, there were higher score in fatigue, nausea and vomiting, diarrhea and financial difficulties.4. There were significant differences among different gender, habitat, education level,economic and the way of medical payment in CD-RISC and the score of health-promoting behaviors(P<0.01 or P<0.05). However, there was no significant differences among different age group, profession, staging of disease and treatments in CD-RISC and the score of health-promoting behaviors(all P>0.05). There was statistical difference among different gender, habitat, education level and economic in the score of general quality of life(P<0.05).5. Resilience had an obvious positive correlation with the health-promoting behaviorsand quality of life(r=0.695, 0.246, all P<0.01).6. Tenacity dimension, payment of medical cost and strength dimension predicted higher level of health-promoting behaviors, and they can explain 54.5% of total variation.Tenacity dimension, and payment of medical cost also predicted higher level of quality of life, and they can explain 40.7% of total variation.Conclusion1. Rectal cancer patients receiving neoadjuvant therapy have low resilience level. There were significant differences among different gender, habitat, education level, economic and the way of medical payment in CD-RISC. So we should pay more attention to the patients who are women or who have lower education level, lower income, and have been in rural and town for a long time.2. Rectal cancer patients receiving neoadjuvant therapy have low score of health-promoting behaviors, especially in health responsibility dimension and physical activity dimension.Resilience had an obvious positive correlation with the health-promoting behaviors. The patients with public payment of medical cost and high resilience level have more possibility to adopt health-promoting behaviors.3. Rectal cancer patients receiving neoadjuvant therapy have low quality of life level.Resilience had an obvious positive correlation with quality of life. The patients with public payment of medical cost and high resilience level have more possibility to experience higher quality of life.