| PurposeThis study conducts a detailed and systematic research of early diagnosis of peripheral facial neuritis. The aim is to provide scientific basis for early diagnosis of peripheral facial neuritis patients, and improve the probability of detecting positive rate and prognosis judgement. These can be achieved through the following: 1) applying neurophysiological F wave examination and comparing the differences of F wave related indicators between ipsilateral and contralateral sides; 2) systematic analysing of the two methods(F wave and blink reflex spread) for peripheral facial neuritis Prognostic; 3) analysing F wave indicators(including F wave latency average, minimum and maximum value, and F wave occurrence rate) and other early important diagnostic marker of peripheral facial neuritis.MethodsWe selected 318 peripheral facial paralysis patients who had treatment at the First Hospital of Lanzhou University, Department of Neurology outpatient and inpatient from March 2012 to June 2015. The sample was divided into two groups. Each group has 160 and 158 cases. We used Keypoint EMG evoked potential produced by Danish for inspection. The first group of patients received F wave examination, and the inspection indicators are F wave latency average, minimum maximum values, and F wave occurrence rate. The second group of patients received blink reflex spread examination. The two groups of patients were then treated for 6 month. And their cure rate and prognosis accuracy rate were compared after 6 month.Results1. For the 48 cases of severe patients, ipsilateral side F wave did not exist and contralateral side F wave existed. Two sides F wave indicators(latency average, minimum and maximum values, and occurrence rate) showed significance differences. 2. For the 112 cases of mild to moderate patients, ipsilateral side F wave existed and it(latency average, minimum and maximum values) was significantly longer than the contralateral side F wave. The F wave’s occurrence rate reduced significantly. And these results were statistically significant(P <0.05).3. F wave and blink reflex early diagnosis in 160 and 158 cases of facial paralysis patients detected,The total effective rate of the two groups was not significantly different(P> 0.05). 4. The patients were visited after six months to evaluate the effects of treatment and rehabilitation by facial nerve function evaluation. The F wave group recovered 88 cases. 45 cases were effective. The total effective rate was 83.01%. And the prognostic evaluation of accuracy is 84.90%. The blink reflex group recovered 66 cases. 60 cases were effective. The total effective rate was 83.01%. And the prognostic evaluation of accuracy is 73.58%. The number of patients recovered in F wave group was more than the blink reflex group. And the difference between the two group are statistically significant differences(P <0.05). The total effective rate of the two groups was not significantly different(P> 0.05). F wave prognostic evaluation of accuracy was significantly higher than the blink reflex group, and this difference are statistically significant(P <0.05).ConclusionAs a diagnosis method of peripheral facial neuritis sensitive nerve electrophysiological examination, Facial nerve F wave has an important value in early diagnosis of peripheral facial paralysis. Blink reflex belongs to a brainstem reflex. Its examination on the central and peripheral facial nerve is abnormal, can accurately diagnose early facial paralysis, But F wave is strong stimulation from the inspection,Sensitive to amplitude change the blink reflex,In terms of prognostic accuracy is better than blink reflex.Facial nerve F provides a reliable scientific basis for early diagnosis of peripheral facial neuritis. The indicators from F-wave(including F-wave latency average minimum and maximum values, F wave occurrence rate), has important value in the diagnosis, early treatment and improving the prognosis. |
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