| Purpose:This study is about evaluating follicular development effect of calming heart and nourishing kidney treating infertile women with polycystic ovary syndrome. To explore the effects of calming heart and nourishing kidney in order to provide new evidence for clinical study.Method:This study collects 60 Kidney deficiency type infertile patients with polycystic ovary syndrome and divides them into the two group, the treatment group 30 cases, and control group 30 cases. The treatment group applies calming heart and nourishing kidney; and the control group applies nourishing kidney in late menstruation for three menstrual cycle of each therapy. Through compared by observed before and after treatment in patients with follicular development,endometrial thickness,BBT, traditional Chinese medicine symptom, menstrual cycle, menstrual score and other indicators.Results:There is no different between two groups in age, menstruation, sex hormone levels, BMI, and other related indicators, no statistical difference, comparable.Change of ovarian follicle and endometrial thickness:The treatment group has a higher response rate on promoted the size of follicles than the treatment group (P<0.05). But, they have almost response rate on endometrial thickness and have no significant difference (P> 0.05).Change of BBT:The two groups both recovery double phase of BBT(P<0.05). The treatment group was better than the control group, but there is no significant difference (P> 0.05).Change of pregnant:The treatment group’pregnancy rate is 30.00%. The control group’ pregnancy rate is 10.00%.The treatment group is higher than the control group and there is significant difference (P>0.05).Change of menstrual score:The treatment group has a higher response rate on reduced menstrual score than the treatment group (P<0.05). But, they have almost response rate on menstrual cycle (P>0.05).Change of TCM syndrome score:The treatment group has a higher response rate on reduced TCM syndrome score than the treatment group (P<0.05).General clinic effect:The treatment group’ total effective rate was 83.33%,while the control’ group total effective rate was 73.33%. The general clinic effect of the treatment group was better than the control group (P<0.05).Safety observation:During the test, the two groups of patients were not found in liver and kidney dysfunction and significant adverse reactions during the test.Conclusion:The treatment of calming heart and nourishing kidney is more effective for pregnant women with polycystic ovary syndrome. It can promote the size of follicles and endometrial growth, shorten inter-menstrual period, and improve pregnancy rate and TCM syndrome. In the same time, it is high safety. It can be further promotion in clinical. |
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