| ObjectiveStudy on clinical features of inpatient Kawasaki disease cases in YanchengCity from 2011 to 2015, especially including the clinical clues for incomplete KD and the risk factors of coronary artery lesion (CAL), in order to improve the level of diagnosis and treatment for KD.MethodsRetrospective analysis of the clinical data of inpatient KD cases from 2011 to 2015 in YanchengCity including Yancheng First People’s Hospital, Maternal and Child Health Care Hospital of Yancheng City and Yancheng Third People’s Hospital, three tertiary hospitals in the city. Using SPSS 19.0 statistical software for statistical analysis, count data with N or percentage (%), using the chi square test, measurement data using t test, the data with mean±standard deviation (x ± s). The risk factors of CAL were analyzed by single factor analysis, screening out the statistically significant variables, and then the multiple factors Logistic regression analysis, P< 0.05 indicated that the difference was statistically significant.Results(1) In all 201 cases, the number of cases has increased year by year, a total of 22 cases in 2011, a total of 23 cases in 2012, a total of 46 cases in 2013, a total of 54 cases in 2014, a total of cases in 2015, a total of 56 cases in 2015.(2) KD can occur throughout the year, (March to May) (63 cases of the four seasons in a year springs,31.3%), summer (June to August) (62 cases, accounted for 30.8%), autumn (September to November) (38 cases, accounted for 18.9%), winter (December to February) (38 cases.accounted for 18.9%). Visible 5-6 month is the peak of incidence, the lowest incidence rate in November. The incidence rate of spring and summer is higher than that of autumn and winter, the highest incidence rate of spring and summer.(3) 201 cases (63.2%) were male (127),74 cases (36.8%), the ratio of male to female was 1.72:1, and the incidence rate of boys in each age group was higher than that of girls.(4) The clinical symptoms appear frequency from high to low in order for fever (100%), conjunctival hyperemia (90.0%), oral mucosal changes (89.0%) and pleomorphic rash (73.1%), limb end change (72.5%), cervical lymph node enlargement (53.0%), perianal skin (34.0%), the BCG scar redness (16.5%).(5) KD and incomplete KD group:age (< 6 month KD, incomplete KD is higher than complete KD.(6) In addition to the perianal skin, scar red card, the rest of the completely in the KD group were higher than incomplete KD group.(7) Male,< 1 year old, the total heating time> 10 days, leukocyte (white blood cell, WBC), platelet (PLT), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), erythrocyte sedimentation rate (ESR) increased and hemoglobin (hemoglobin, HB) decline is associated with the occurrence of cal. Multivariate logistic regression analysis showed that age< 1 year old, the total heating time> 10 days, PLT increased, increased ESR and KD with cal significantly and independently associated.Conclusion(1) The number of hospitalized cases of KD in Yancheng increased year by year, and the age of patients was less than 5 years old. The incidence of boys in different age groups was higher than that of girls. In addition to fever, the main clinical manifestations of the most common conjunctival congestion.(2)Incomplete KD in children with high incidence of the disease in June.(3)age< 1 years old, the total number of hot days> 10 days, PLT, ESR may be an independent risk factor for CAL. |
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