Advanced Non-small Cell Lung Cancer Before And After Treatment With Gefitinib TCM Syndrome Distribution Characteristics And Evolution

Purposes:This topic prospective study, patients with advanced non-small cell lung cancer patients were treated with gefitinib after treatment syndromes depth and detailed study to investigate the distribution and evolution of syndromes characterized before and after lung cancer targeted therapy, and that "early intervention "the idea, to provide research data for Chinese medicine with the best time targeted therapies to improve the efficacy of Chinese and Western medicine treatment of lung cancer optimal combination of new research ideas.Methods:Select from March 2015 to February 2016 Check Jiangsu Provincial Hospital, patients with lung cancer in Jiangsu Province Tumor Hospital outpatient wards and 50 cases of advanced non-small cell. TCM syndrome before and after the recording of oral gefitinib treatment through the questionnaire form.Result:(1) pre-treatment targeting common cough, malaise, fatigue, sputum viscosity, spontaneous, low sodium and other symptoms, pink tongue to tongue, scalloped tongue and thin white fur common, accounting for 58%,40%,52%, pulse common veinlets, slippery pulse, respectively 40%,30%, to qi deficiency syndrome distribution and phlegm main card, accounting 44%,28%; (2) targeted treatment d15 days after fever, night sweats, five upset hot, dry mouth and other symptoms compared with the previous increase, tongue red tongue, little coating based, respectively,38%,58%, pulse common breakdown pulse,54%, to Qi deficiency Syndrome distribution and deficiency heat syndrome, accounting for 32%, respectively,26%; (3) targeted therapy d30 deficiency symptoms, tongue and pulse distribution compared with the previous indifference, yin deficiency syndrome increased to 38%. Statistical results obtained, no significant differences targeting syndrome distribution d15 d30 after treatment and therapy.Conclusion:Before and after gefitinib targeted therapy TCM Syndrome evolution there is a pattern. Before treatment with qi deficiency and phlegm main card, a significant increase compared with that before treatment Qi Deficiency, deficiency heat syndrome after treatment table gefitinib is toxic heat of the goods, gas consumption Shangyin, and to increase the blood stasis of the elephant. Prompt us to imatinib targeted therapy gefitinib before and early intervention to Qi Yin, detoxification-based, and accompanied by a small amount of blood circulation of goods.